ENSMUSG00000008167

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENSMUST00000095220 ENSMUSG00000008167 Control shVgll3 Fbxw9 protein_coding protein_coding 5.64313 5.798 5.48826 0.3212403 0.4198343 -0.07906625 2.1578589 1.82737518 2.4883426 1.21200101 0.64006102 0.4433251 0.38515000 0.297200000 0.47310000 0.17590000 0.970665669 0.004076898 FALSE  
ENSMUST00000125109 ENSMUSG00000008167 Control shVgll3 Fbxw9 protein_coding retained_intron 5.64313 5.798 5.48826 0.3212403 0.4198343 -0.07906625 0.1972993 0.39459852 0.0000000 0.39459852 0.00000000 -5.3384192 0.03258333 0.065166667 0.00000000 -0.06516667 0.970665669 0.004076898 FALSE  
ENSMUST00000139721 ENSMUSG00000008167 Control shVgll3 Fbxw9 protein_coding retained_intron 5.64313 5.798 5.48826 0.3212403 0.4198343 -0.07906625 1.4296614 2.00222908 0.8570937 1.11321054 0.53126658 -1.2145348 0.25658333 0.367433333 0.14573333 -0.22170000 0.970665669 0.004076898 TRUE  
ENSMUST00000141183 ENSMUSG00000008167 Control shVgll3 Fbxw9 protein_coding retained_intron 5.64313 5.798 5.48826 0.3212403 0.4198343 -0.07906625 0.5797936 0.45984617 0.6997410 0.09764493 0.32977187 0.5951041 0.09956667 0.078233333 0.12090000 0.04266667 0.970665669 0.004076898    
ENSMUST00000145479 ENSMUSG00000008167 Control shVgll3 Fbxw9 protein_coding retained_intron 5.64313 5.798 5.48826 0.3212403 0.4198343 -0.07906625 0.1782793 0.35655864 0.0000000 0.10736683 0.00000000 -5.1959721 0.03000000 0.060000000 0.00000000 -0.06000000 0.004076898 0.004076898 FALSE  
ENSMUST00000151962 ENSMUSG00000008167 Control shVgll3 Fbxw9 protein_coding retained_intron 5.64313 5.798 5.48826 0.3212403 0.4198343 -0.07906625 0.4505212 0.22589428 0.6751482 0.11974811 0.07629005 1.5382755 0.08176667 0.040900000 0.12263333 0.08173333 0.617440452 0.004076898    
MSTRG.22635.6 ENSMUSG00000008167 Control shVgll3 Fbxw9 protein_coding   5.64313 5.798 5.48826 0.3212403 0.4198343 -0.07906625 0.2117554 0.04882413 0.3746868 0.04882413 0.29159789 2.7092041 0.03596667 0.008066667 0.06386667 0.05580000 0.970665669 0.004076898 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand shVgll3 Control log2fold_Control_shVgll3
ENSMUSG00000008167 E001 0.1657302 0.0344704288 0.531323580   8 85786684 85786684 1 + 0.000 0.119 9.690
ENSMUSG00000008167 E002 0.4928139 0.1790376993 0.676281476   8 85786685 85786725 41 + 0.128 0.213 0.890
ENSMUSG00000008167 E003 14.6476189 0.0014502136 0.247774223 0.8048480 8 85786726 85787157 432 + 1.135 1.242 0.378
ENSMUSG00000008167 E004 3.7850850 0.0046580643 0.002568176 0.0922663 8 85787158 85787165 8 + 0.375 0.846 2.135
ENSMUSG00000008167 E005 0.4933529 0.0350293455 0.100907808   8 85787166 85787195 30 + 0.000 0.290 13.325
ENSMUSG00000008167 E006 8.3845913 0.0023602518 0.631094972 0.9562377 8 85787196 85787979 784 + 0.996 0.950 -0.170
ENSMUSG00000008167 E007 6.2457227 0.0413186519 0.092247119 0.6270231 8 85788575 85788596 22 + 0.708 0.965 1.004
ENSMUSG00000008167 E008 15.4424120 0.0306077800 0.373584646 0.8783467 8 85788597 85788714 118 + 1.156 1.265 0.384
ENSMUSG00000008167 E009 19.5408734 0.0020802283 0.502139822 0.9278351 8 85788801 85788929 129 + 1.282 1.340 0.203
ENSMUSG00000008167 E010 13.1761513 0.0020226276 0.251547166 0.8064151 8 85791013 85791125 113 + 1.090 1.201 0.397
ENSMUSG00000008167 E011 5.7783109 0.0046462656 0.115025549 0.6599920 8 85791126 85791209 84 + 0.708 0.918 0.826
ENSMUSG00000008167 E012 4.9475040 0.0053199776 0.643648235 0.9566871 8 85791210 85791223 14 + 0.736 0.805 0.274
ENSMUSG00000008167 E013 9.5681362 0.0063941790 0.681897352 0.9628980 8 85791224 85791301 78 + 0.996 1.046 0.186
ENSMUSG00000008167 E014 1.6370651 0.0116260260 0.073126982 0.5803859 8 85791302 85791441 140 + 0.226 0.548 1.887
ENSMUSG00000008167 E015 0.3274496 0.0264086408 0.226350823   8 85792197 85792247 51 + 0.000 0.213 12.825
ENSMUSG00000008167 E016 2.4701199 0.0077033051 0.142803449 0.7090546 8 85792251 85792449 199 + 0.646 0.412 -1.113
ENSMUSG00000008167 E017 16.9827331 0.0012777213 0.558375472 0.9411047 8 85792450 85792598 149 + 1.274 1.234 -0.141
ENSMUSG00000008167 E018 4.9439569 0.0251485871 0.151064493 0.7185630 8 85792685 85792691 7 + 0.646 0.865 0.886
ENSMUSG00000008167 E019 21.7421628 0.0009338161 0.203002462 0.7776243 8 85792692 85792798 107 + 1.397 1.314 -0.288
ENSMUSG00000008167 E020 4.9421924 0.0110413001 0.540106123 0.9366248 8 85792799 85792901 103 + 0.811 0.735 -0.306
ENSMUSG00000008167 E021 26.1691075 0.0007239726 0.063234779 0.5463223 8 85792902 85792991 90 + 1.488 1.376 -0.386
ENSMUSG00000008167 E022 1.1590248 0.0173758707 0.623712881 0.9551420 8 85792992 85793073 82 + 0.375 0.290 -0.528
ENSMUSG00000008167 E023 17.9227616 0.0039850259 0.690839157 0.9629190 8 85793074 85793139 66 + 1.290 1.265 -0.087
ENSMUSG00000008167 E024 0.6646527 0.0198573696 0.271941471   8 85793140 85793218 79 + 0.307 0.119 -1.698
ENSMUSG00000008167 E025 57.6287625 0.0005390827 0.021830142 0.3331657 8 85793219 85793753 535 + 1.811 1.723 -0.295

Help

Please Click HERE to learn more details about the results from DEXseq.