ENSMUSG00000014791

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENSMUST00000109375 ENSMUSG00000014791 Control shVgll3 Elmo3 protein_coding protein_coding 2.100441 2.555968 1.644913 0.5098725 0.2203745 -0.6327475 0.1474492 0.07433471 0.2205638 0.04844829 0.052040117 1.4509673 0.08138333 0.02530000 0.13746667 0.11216667 0.44384954 0.00439838 FALSE TRUE
ENSMUST00000212046 ENSMUSG00000014791 Control shVgll3 Elmo3 protein_coding nonsense_mediated_decay 2.100441 2.555968 1.644913 0.5098725 0.2203745 -0.6327475 0.4191059 0.44512383 0.3930880 0.08032129 0.002484409 -0.1751644 0.22878333 0.20910000 0.24846667 0.03936667 0.97066567 0.00439838 FALSE TRUE
ENSMUST00000212655 ENSMUSG00000014791 Control shVgll3 Elmo3 protein_coding retained_intron 2.100441 2.555968 1.644913 0.5098725 0.2203745 -0.6327475 0.4443846 0.88876912 0.0000000 0.36476309 0.000000000 -6.4898787 0.15433333 0.30866667 0.00000000 -0.30866667 0.00439838 0.00439838   FALSE
MSTRG.22827.5 ENSMUSG00000014791 Control shVgll3 Elmo3 protein_coding   2.100441 2.555968 1.644913 0.5098725 0.2203745 -0.6327475 0.3432826 0.26302361 0.4235416 0.12537635 0.101863814 0.6671447 0.19500000 0.13980000 0.25020000 0.11040000 0.95734744 0.00439838 FALSE TRUE
MSTRG.22827.7 ENSMUSG00000014791 Control shVgll3 Elmo3 protein_coding   2.100441 2.555968 1.644913 0.5098725 0.2203745 -0.6327475 0.2132276 0.16933064 0.2571245 0.13664826 0.154090430 0.5748902 0.11516667 0.05946667 0.17086667 0.11140000 0.97066567 0.00439838 FALSE FALSE
MSTRG.22827.8 ENSMUSG00000014791 Control shVgll3 Elmo3 protein_coding   2.100441 2.555968 1.644913 0.5098725 0.2203745 -0.6327475 0.3187927 0.49488602 0.1426994 0.24822411 0.142699403 -1.7252633 0.11645000 0.16246667 0.07043333 -0.09203333 0.97066567 0.00439838   FALSE
MSTRG.22827.9 ENSMUSG00000014791 Control shVgll3 Elmo3 protein_coding   2.100441 2.555968 1.644913 0.5098725 0.2203745 -0.6327475 0.1762237 0.14455131 0.2078960 0.05249285 0.122275941 0.4955539 0.08928333 0.05600000 0.12256667 0.06656667 0.97066567 0.00439838 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand shVgll3 Control log2fold_Control_shVgll3
ENSMUSG00000014791 E001 1.6414318 0.013691553 0.0005185849 0.02888765 8 106032233 106032240 8 + 0.000 0.633 12.422
ENSMUSG00000014791 E002 1.9732486 0.008773220 0.0024085259 0.08832268 8 106032241 106032244 4 + 0.123 0.665 3.465
ENSMUSG00000014791 E003 2.6328713 0.048681908 0.0223262469 0.33645342 8 106032245 106032274 30 + 0.298 0.723 2.121
ENSMUSG00000014791 E004 5.9293140 0.003276227 0.8280552341 0.98548395 8 106032275 106032461 187 + 0.818 0.861 0.166
ENSMUSG00000014791 E005 1.1487226 0.012556851 0.6720226965 0.96111497 8 106032599 106032628 30 + 0.364 0.299 -0.409
ENSMUSG00000014791 E006 0.8266786 0.017976582 0.6903179463 0.96291900 8 106032629 106032639 11 + 0.219 0.299 0.591
ENSMUSG00000014791 E007 0.9917958 0.377096702 0.6793851012 0.96217875 8 106032698 106032746 49 + 0.365 0.220 -0.999
ENSMUSG00000014791 E008 2.2932803 0.016336451 0.1300952969 0.68706453 8 106032747 106032819 73 + 0.364 0.633 1.328
ENSMUSG00000014791 E009 0.6587172 0.023972747 0.3306528069   8 106032977 106033009 33 + 0.123 0.299 1.591
ENSMUSG00000014791 E010 1.8086517 0.009050061 0.8132508162 0.98376893 8 106033010 106033060 51 + 0.422 0.474 0.269
ENSMUSG00000014791 E011 3.7811488 0.005057095 0.3397826863 0.86886794 8 106033061 106033227 167 + 0.597 0.749 0.644
ENSMUSG00000014791 E012 6.4070925 0.003032513 0.7135582068 0.96841481 8 106033228 106033397 170 + 0.840 0.899 0.228
ENSMUSG00000014791 E013 4.2541309 0.122105761 0.3650477457 0.87540223 8 106033398 106033472 75 + 0.597 0.819 0.919
ENSMUSG00000014791 E014 1.9655636 0.116929019 0.1693171946 0.74790655 8 106033473 106033485 13 + 0.298 0.598 1.586
ENSMUSG00000014791 E015 4.4270666 0.006955872 0.0422773140 0.46092332 8 106033486 106033585 100 + 0.560 0.861 1.254
ENSMUSG00000014791 E016 5.9327364 0.003337158 0.6521762937 0.95668705 8 106033671 106033822 152 + 0.860 0.820 -0.154
ENSMUSG00000014791 E017 1.8022169 0.011333339 0.8090052200 0.98304176 8 106033823 106033919 97 + 0.422 0.474 0.270
ENSMUSG00000014791 E018 2.1380244 0.549219432 0.4000881402 0.89038940 8 106033920 106033929 10 + 0.362 0.600 1.196
ENSMUSG00000014791 E019 3.9409061 0.004558736 0.1865947156 0.76391936 8 106033930 106033998 69 + 0.773 0.599 -0.731
ENSMUSG00000014791 E020 3.1202768 0.005619364 0.0075603755 0.18978814 8 106034095 106034145 51 + 0.773 0.365 -1.901
ENSMUSG00000014791 E021 0.9964695 0.270831118 0.4931516977 0.92674629 8 106034146 106034194 49 + 0.365 0.220 -0.996
ENSMUSG00000014791 E022 0.8258426 0.018031394 0.6881018477 0.96291900 8 106034195 106034226 32 + 0.219 0.299 0.591
ENSMUSG00000014791 E023 3.6115914 0.005177098 0.3490045531 0.87508037 8 106034227 106034349 123 + 0.722 0.599 -0.524
ENSMUSG00000014791 E024 0.6547164 0.019189131 0.9720261708   8 106034350 106034433 84 + 0.219 0.220 0.006
ENSMUSG00000014791 E025 0.0000000       8 106034434 106034514 81 +      
ENSMUSG00000014791 E026 2.1490294 0.032380773 0.4715506743 0.92105523 8 106034515 106034565 51 + 0.422 0.561 0.684
ENSMUSG00000014791 E027 2.9600788 0.005998085 0.0670673643 0.55809015 8 106034566 106034665 100 + 0.422 0.723 1.385
ENSMUSG00000014791 E028 4.9157515 0.007147166 0.9286045912 0.99930331 8 106034666 106034767 102 + 0.773 0.774 0.006
ENSMUSG00000014791 E029 1.9784225 0.010630970 0.6148898480 0.95421876 8 106034768 106034863 96 + 0.422 0.520 0.492
ENSMUSG00000014791 E030 4.6095395 0.006890360 0.6318924471 0.95623770 8 106034864 106034972 109 + 0.773 0.723 -0.200
ENSMUSG00000014791 E031 2.9755056 0.126281843 0.5983457062 0.95239194 8 106035081 106035217 137 + 0.632 0.562 -0.313
ENSMUSG00000014791 E032 6.5870330 0.014868793 0.1114785166 0.65453028 8 106035304 106035467 164 + 0.964 0.774 -0.731
ENSMUSG00000014791 E033 6.0972167 0.003520077 0.0513145117 0.49442254 8 106035554 106035666 113 + 0.948 0.723 -0.879
ENSMUSG00000014791 E034 1.1537622 0.013826349 0.7460914024 0.97314738 8 106035667 106035745 79 + 0.298 0.365 0.421
ENSMUSG00000014791 E035 3.7930199 0.004939030 0.4732311552 0.92123094 8 106035746 106035850 105 + 0.722 0.633 -0.373
ENSMUSG00000014791 E036 3.7659120 0.015874375 0.7716272326 0.97799068 8 106035957 106036039 83 + 0.694 0.665 -0.120
ENSMUSG00000014791 E037 6.4200564 0.006151716 0.3578702967 0.87517695 8 106036125 106036211 87 + 0.915 0.820 -0.366
ENSMUSG00000014791 E038 18.8998942 0.001158819 0.0358225400 0.42724341 8 106036297 106037392 1096 + 1.362 1.226 -0.475

Help

Please Click HERE to learn more details about the results from DEXseq.