ENSMUSG00000015165

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENSMUST00000038572 ENSMUSG00000015165 Control shVgll3 Hnrnpl protein_coding protein_coding 98.0612 95.57734 100.5451 1.940705 3.241058 0.07309418 7.544430 4.871354 10.217505 2.8669884 1.8830653 1.06710084 0.07636667 0.05073333 0.10200000 0.05126667 0.9706656688 0.0001233878 FALSE  
ENSMUST00000172529 ENSMUSG00000015165 Control shVgll3 Hnrnpl protein_coding protein_coding 98.0612 95.57734 100.5451 1.940705 3.241058 0.07309418 38.565305 33.810723 43.319888 2.9585081 3.4460831 0.35745501 0.39196667 0.35426667 0.42966667 0.07540000 0.8267959491 0.0001233878 FALSE  
ENSMUST00000173750 ENSMUSG00000015165 Control shVgll3 Hnrnpl protein_coding retained_intron 98.0612 95.57734 100.5451 1.940705 3.241058 0.07309418 9.103708 12.326759 5.880658 2.0608947 3.3993654 -1.06646286 0.09408333 0.12840000 0.05976667 -0.06863333 0.9706656688 0.0001233878 FALSE  
ENSMUST00000174477 ENSMUSG00000015165 Control shVgll3 Hnrnpl protein_coding protein_coding 98.0612 95.57734 100.5451 1.940705 3.241058 0.07309418 15.331258 18.695093 11.967423 0.3447574 0.6132853 -0.64311361 0.15756667 0.19580000 0.11933333 -0.07646667 0.0001233878 0.0001233878 FALSE  
ENSMUST00000174755 ENSMUSG00000015165 Control shVgll3 Hnrnpl protein_coding retained_intron 98.0612 95.57734 100.5451 1.940705 3.241058 0.07309418 5.748080 2.198884 9.297275 2.1988838 3.7426095 2.07504136 0.05761667 0.02366667 0.09156667 0.06790000 0.6053539504 0.0001233878 FALSE  
MSTRG.20442.2 ENSMUSG00000015165 Control shVgll3 Hnrnpl protein_coding   98.0612 95.57734 100.5451 1.940705 3.241058 0.07309418 9.483227 9.277516 9.688939 0.8818077 0.9314256 0.06253419 0.09733333 0.09753333 0.09713333 -0.00040000 1.0000000000 0.0001233878 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand shVgll3 Control log2fold_Control_shVgll3
ENSMUSG00000015165 E001 0.3274400 0.0260267196 2.240644e-01   7 28507966 28508230 265 + 0.212 0.000 -11.905
ENSMUSG00000015165 E002 0.1613534 0.0345417289 5.268272e-01   7 28508231 28508232 2 + 0.119 0.000 -10.904
ENSMUSG00000015165 E003 0.1613534 0.0345417289 5.268272e-01   7 28508233 28508244 12 + 0.119 0.000 -10.904
ENSMUSG00000015165 E004 8.7362507 0.0022725593 6.529651e-01 9.566871e-01 7 28508245 28508284 40 + 0.962 1.013 0.187
ENSMUSG00000015165 E005 0.0000000       7 28508943 28508974 32 +      
ENSMUSG00000015165 E006 3.6104380 0.0051723482 5.795028e-02 5.234760e-01 7 28510097 28510314 218 + 0.505 0.790 1.233
ENSMUSG00000015165 E007 5.0966696 0.0966541519 1.458342e-01 7.112720e-01 7 28510315 28510361 47 + 0.617 0.916 1.206
ENSMUSG00000015165 E008 4.4375864 0.1202264173 3.458793e-01 8.733209e-01 7 28510362 28510364 3 + 0.617 0.836 0.901
ENSMUSG00000015165 E009 111.4504299 0.0021864266 4.543958e-01 9.139571e-01 7 28510365 28510593 229 + 2.063 2.036 -0.093
ENSMUSG00000015165 E010 156.2955182 0.0003723900 6.456871e-02 5.507372e-01 7 28512704 28512769 66 + 2.220 2.168 -0.175
ENSMUSG00000015165 E011 148.0750112 0.0027280526 8.880929e-03 2.042115e-01 7 28512770 28512802 33 + 2.217 2.118 -0.331
ENSMUSG00000015165 E012 87.5424210 0.0002427474 3.224094e-03 1.077584e-01 7 28512803 28512822 20 + 1.996 1.885 -0.371
ENSMUSG00000015165 E013 556.4101942 0.0001176787 7.371131e-05 5.865816e-03 7 28513279 28513516 238 + 2.772 2.714 -0.193
ENSMUSG00000015165 E014 232.4387428 0.0006594864 8.523486e-01 9.881019e-01 7 28513627 28513712 86 + 2.369 2.366 -0.010
ENSMUSG00000015165 E015 12.5080795 0.0868284138 8.050399e-01 9.821080e-01 7 28513713 28513872 160 + 1.144 1.115 -0.103
ENSMUSG00000015165 E016 21.2141439 0.0025410550 8.205887e-01 9.841109e-01 7 28514249 28514523 275 + 1.337 1.356 0.066
ENSMUSG00000015165 E017 176.9625249 0.0001637457 4.627939e-01 9.180740e-01 7 28514524 28514530 7 + 2.239 2.261 0.071
ENSMUSG00000015165 E018 358.7162569 0.0001224663 6.419522e-01 9.566871e-01 7 28514531 28514620 90 + 2.559 2.552 -0.023
ENSMUSG00000015165 E019 333.5486207 0.0004824892 2.946633e-01 8.382980e-01 7 28514705 28514777 73 + 2.534 2.513 -0.069
ENSMUSG00000015165 E020 664.8804793 0.0009976301 2.764778e-01 8.218390e-01 7 28514778 28516385 1608 + 2.812 2.835 0.075
ENSMUSG00000015165 E021 33.7312212 0.0005384529 2.146553e-01 7.879665e-01 7 28516760 28516829 70 + 1.502 1.578 0.260
ENSMUSG00000015165 E022 130.5479038 0.0049419294 9.222696e-01 9.979465e-01 7 28516830 28517258 429 + 2.115 2.122 0.021
ENSMUSG00000015165 E023 243.8682356 0.0001648959 3.751359e-04 2.285593e-02 7 28517259 28517885 627 + 2.347 2.430 0.277
ENSMUSG00000015165 E024 293.8252061 0.0003409578 9.791399e-01 1.000000e+00 7 28517886 28517957 72 + 2.469 2.470 0.004
ENSMUSG00000015165 E025 73.3391640 0.0002740326 1.193536e-08 2.849384e-06 7 28517958 28518068 111 + 1.741 1.980 0.805
ENSMUSG00000015165 E026 646.1893044 0.0035060571 5.375344e-01 9.366248e-01 7 28518069 28518349 281 + 2.802 2.820 0.062
ENSMUSG00000015165 E027 193.5693797 0.0001517525 1.834721e-02 3.061708e-01 7 28519578 28519699 122 + 2.258 2.320 0.207
ENSMUSG00000015165 E028 6.7486419 0.0065666846 2.559417e-02 3.585635e-01 7 28519700 28519969 270 + 0.732 1.013 1.081
ENSMUSG00000015165 E029 593.0615794 0.0005234998 7.732727e-01 9.780868e-01 7 28519970 28520171 202 + 2.770 2.777 0.022
ENSMUSG00000015165 E030 1.3141463 0.0132586072 5.647248e-01 9.421718e-01 7 28520638 28520640 3 + 0.410 0.308 -0.604
ENSMUSG00000015165 E031 303.1409582 0.0009986885 3.604728e-01 8.753500e-01 7 28520641 28520698 58 + 2.471 2.495 0.081
ENSMUSG00000015165 E032 3.4490942 0.0051082067 2.014275e-03 7.964488e-02 7 28520699 28520816 118 + 0.354 0.836 2.220
ENSMUSG00000015165 E033 352.7919610 0.0001111442 4.317498e-01 9.086419e-01 7 28520817 28520912 96 + 2.554 2.541 -0.044
ENSMUSG00000015165 E034 377.7748997 0.0001177282 9.798512e-02 6.331714e-01 7 28521273 28521691 419 + 2.591 2.563 -0.095

Help

Please Click HERE to learn more details about the results from DEXseq.