ENSMUSG00000020311

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENSMUST00000073192 ENSMUSG00000020311 Control shVgll3 Erlec1 protein_coding protein_coding 30.22218 33.26266 27.18171 1.493402 0.81576 -0.2911703 3.3050482 4.047705 2.562391 0.2370692 0.09833000 -0.65755397 0.10810000 0.12160000 0.09460000 -0.027000000 6.199636e-01 4.838809e-17 FALSE  
ENSMUST00000129593 ENSMUSG00000020311 Control shVgll3 Erlec1 protein_coding nonsense_mediated_decay 30.22218 33.26266 27.18171 1.493402 0.81576 -0.2911703 2.6456534 3.834356 1.456951 1.7217508 1.45695099 -1.38992123 0.08445000 0.11563333 0.05326667 -0.062366667 6.485369e-01 4.838809e-17 TRUE  
ENSMUST00000155304 ENSMUSG00000020311 Control shVgll3 Erlec1 protein_coding retained_intron 30.22218 33.26266 27.18171 1.493402 0.81576 -0.2911703 2.3561956 2.396767 2.315624 0.2760297 0.29176150 -0.04947869 0.07898333 0.07280000 0.08516667 0.012366667 9.706657e-01 4.838809e-17 FALSE  
MSTRG.3284.1 ENSMUSG00000020311 Control shVgll3 Erlec1 protein_coding   30.22218 33.26266 27.18171 1.493402 0.81576 -0.2911703 5.5495117 5.252165 5.846859 0.2071045 0.14789404 0.15447065 0.18690000 0.15826667 0.21553333 0.057266667 1.915136e-01 4.838809e-17 FALSE  
MSTRG.3284.3 ENSMUSG00000020311 Control shVgll3 Erlec1 protein_coding   30.22218 33.26266 27.18171 1.493402 0.81576 -0.2911703 1.8120727 1.688186 1.935959 0.1223222 0.08086907 0.19648637 0.06110000 0.05066667 0.07153333 0.020866667 6.174405e-01 4.838809e-17 TRUE  
MSTRG.3284.4 ENSMUSG00000020311 Control shVgll3 Erlec1 protein_coding   30.22218 33.26266 27.18171 1.493402 0.81576 -0.2911703 0.8236225 0.000000 1.647245 0.0000000 0.22590906 7.37264314 0.03018333 0.00000000 0.06036667 0.060366667 4.838809e-17 4.838809e-17 FALSE  
MSTRG.3284.5 ENSMUSG00000020311 Control shVgll3 Erlec1 protein_coding   30.22218 33.26266 27.18171 1.493402 0.81576 -0.2911703 4.8625755 5.853931 3.871220 0.7568406 0.57354361 -0.59535792 0.16003333 0.17780000 0.14226667 -0.035533333 9.706657e-01 4.838809e-17 FALSE  
MSTRG.3284.7 ENSMUSG00000020311 Control shVgll3 Erlec1 protein_coding   30.22218 33.26266 27.18171 1.493402 0.81576 -0.2911703 8.2014527 8.906544 7.496361 0.6014237 0.41471018 -0.24837106 0.27140000 0.26726667 0.27553333 0.008266667 9.856646e-01 4.838809e-17 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand shVgll3 Control log2fold_Control_shVgll3
ENSMUSG00000020311 E001 0.3228996 0.0283140406 0.9317185835   11 30849655 30849664 10 - 0.130 0.118 -0.165
ENSMUSG00000020311 E002 186.3960950 0.0001556715 0.0002017452 0.01356331 11 30849665 30850986 1322 - 2.318 2.227 -0.305
ENSMUSG00000020311 E003 23.3779294 0.0017735453 0.0474740690 0.48105017 11 30863314 30863894 581 - 1.455 1.313 -0.492
ENSMUSG00000020311 E004 13.6505302 0.0013330000 0.0175720430 0.30149090 11 30863895 30864113 219 - 1.265 1.051 -0.765
ENSMUSG00000020311 E005 23.5094102 0.0008188194 0.2969016321 0.84044841 11 30874311 30874540 230 - 1.347 1.423 0.262
ENSMUSG00000020311 E006 37.7522653 0.0067731976 0.0014135838 0.06335672 11 30880774 30881602 829 - 1.455 1.680 0.769
ENSMUSG00000020311 E007 74.4730787 0.0003061179 0.0579407635 0.52347602 11 30881603 30881750 148 - 1.834 1.913 0.265
ENSMUSG00000020311 E008 54.1598910 0.0003919820 0.2348283041 0.80428340 11 30881751 30881848 98 - 1.709 1.767 0.196
ENSMUSG00000020311 E009 66.5753212 0.0101475743 0.4234848420 0.90545038 11 30884672 30884747 76 - 1.800 1.853 0.179
ENSMUSG00000020311 E010 33.5552577 0.0005340650 0.9985350837 1.00000000 11 30884982 30885000 19 - 1.537 1.539 0.005
ENSMUSG00000020311 E011 52.7498540 0.0004028757 0.5080496818 0.93082987 11 30885001 30885059 59 - 1.746 1.716 -0.102
ENSMUSG00000020311 E012 6.9074134 0.0266177908 0.3141843030 0.85211665 11 30885368 30885445 78 - 0.818 0.958 0.535
ENSMUSG00000020311 E013 120.3865359 0.0001917147 0.9149379791 0.99751275 11 30889497 30889621 125 - 2.081 2.086 0.017
ENSMUSG00000020311 E014 15.2951168 0.0012722935 0.3864050591 0.88546179 11 30892682 30893038 357 - 1.249 1.176 -0.258
ENSMUSG00000020311 E015 113.7509070 0.0002066536 0.0815067309 0.59966399 11 30893039 30893098 60 - 2.028 2.086 0.195
ENSMUSG00000020311 E016 194.8743167 0.0008161641 0.5131863815 0.93088142 11 30893699 30893860 162 - 2.281 2.300 0.065
ENSMUSG00000020311 E017 159.3123344 0.0001866611 0.7698151083 0.97799068 11 30898079 30898208 130 - 2.199 2.209 0.032
ENSMUSG00000020311 E018 259.2768460 0.0001757231 0.1169581854 0.66203098 11 30898300 30898523 224 - 2.396 2.431 0.116
ENSMUSG00000020311 E019 58.6409127 0.0005719121 0.0753077284 0.58469696 11 30899943 30899977 35 - 1.729 1.813 0.283
ENSMUSG00000020311 E020 0.4889862 0.0220194497 0.5005877561   11 30899978 30900001 24 - 0.230 0.118 -1.165
ENSMUSG00000020311 E021 72.1472008 0.0002907556 0.4200492595 0.90292838 11 30900560 30900623 64 - 1.880 1.849 -0.106
ENSMUSG00000020311 E022 89.2632808 0.0002535766 0.0225119537 0.33645342 11 30900741 30900818 78 - 1.997 1.914 -0.277
ENSMUSG00000020311 E023 66.2810935 0.0005762995 0.1921998624 0.76838742 11 30901307 30901387 81 - 1.856 1.800 -0.186
ENSMUSG00000020311 E024 62.1669907 0.0022336469 0.0644569480 0.55073725 11 30902572 30902676 105 - 1.845 1.755 -0.302
ENSMUSG00000020311 E025 0.6555524 0.0181785031 0.9075203825   11 30903007 30903116 110 - 0.230 0.210 -0.165
ENSMUSG00000020311 E026 100.5012804 0.0002043592 0.5952227518 0.95165770 11 30903914 30904357 444 - 2.015 1.998 -0.056

Help

Please Click HERE to learn more details about the results from DEXseq.