ENSMUSG00000020836

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENSMUST00000052515 ENSMUSG00000020836 Control shVgll3 Coro6 protein_coding protein_coding 3.05327 3.575988 2.530553 0.217601 0.006388825 -0.4972279 0.17377855 0.0000000 0.3475571 0.00000000 0.17551661 5.160102 0.06885000 0.0000000 0.13770000 0.13770000 0.56442529 0.03542887 FALSE TRUE
ENSMUST00000079770 ENSMUSG00000020836 Control shVgll3 Coro6 protein_coding protein_coding 3.05327 3.575988 2.530553 0.217601 0.006388825 -0.4972279 0.23718991 0.4743798 0.0000000 0.15843596 0.00000000 -5.598067 0.06396667 0.1279333 0.00000000 -0.12793333 0.03542887 0.03542887 FALSE TRUE
ENSMUST00000102493 ENSMUSG00000020836 Control shVgll3 Coro6 protein_coding protein_coding 3.05327 3.575988 2.530553 0.217601 0.006388825 -0.4972279 0.22840438 0.3314986 0.1253102 0.02245343 0.06498904 -1.335609 0.07113333 0.0926000 0.04966667 -0.04293333 0.97066567 0.03542887 FALSE TRUE
ENSMUST00000108391 ENSMUSG00000020836 Control shVgll3 Coro6 protein_coding protein_coding 3.05327 3.575988 2.530553 0.217601 0.006388825 -0.4972279 0.13582850 0.0000000 0.2716570 0.00000000 0.27165701 4.815867 0.05343333 0.0000000 0.10686667 0.10686667 0.97066567 0.03542887 FALSE TRUE
MSTRG.3876.10 ENSMUSG00000020836 Control shVgll3 Coro6 protein_coding   3.05327 3.575988 2.530553 0.217601 0.006388825 -0.4972279 0.75386663 0.8655593 0.6421740 0.07283975 0.05977567 -0.424948 0.24775000 0.2417000 0.25380000 0.01210000 1.00000000 0.03542887 FALSE TRUE
MSTRG.3876.3 ENSMUSG00000020836 Control shVgll3 Coro6 protein_coding   3.05327 3.575988 2.530553 0.217601 0.006388825 -0.4972279 1.40182690 1.9045499 0.8991039 0.03659929 0.06017336 -1.074488 0.44660000 0.5377667 0.35543333 -0.18233333 0.46658887 0.03542887 TRUE TRUE
MSTRG.3876.4 ENSMUSG00000020836 Control shVgll3 Coro6 protein_coding   3.05327 3.575988 2.530553 0.217601 0.006388825 -0.4972279 0.07971965 0.0000000 0.1594393 0.00000000 0.15943929 4.082697 0.03150000 0.0000000 0.06300000 0.06300000 0.97066567 0.03542887 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand shVgll3 Control log2fold_Control_shVgll3
ENSMUSG00000020836 E001 0.0000000       11 77353237 77353402 166 +      
ENSMUSG00000020836 E002 0.4940061 0.0218924437 0.350098072   11 77353403 77353407 5 + 0.261 0.102 -1.643
ENSMUSG00000020836 E003 0.6555524 0.0181200024 0.676167866   11 77353408 77353435 28 + 0.261 0.184 -0.643
ENSMUSG00000020836 E004 2.6375355 0.0066967922 0.493562915 0.9267463 11 77353436 77353470 35 + 0.485 0.591 0.495
ENSMUSG00000020836 E005 5.9339910 0.0438795137 0.335258162 0.8661819 11 77353471 77353580 110 + 0.742 0.880 0.541
ENSMUSG00000020836 E006 1.6478278 0.0105871715 0.508861087 0.9308299 11 77354482 77354549 68 + 0.485 0.365 -0.643
ENSMUSG00000020836 E007 0.4941893 0.0214972899 0.036552802   11 77354662 77354677 16 + 0.349 0.000 -11.232
ENSMUSG00000020836 E008 1.9855010 0.0088856778 0.013906187 0.2619558 11 77354678 77354736 59 + 0.672 0.253 -2.228
ENSMUSG00000020836 E009 1.4871180 0.0107894578 0.002251331 0.0852300 11 77354737 77354754 18 + 0.632 0.102 -3.643
ENSMUSG00000020836 E010 12.1923030 0.0742691824 0.363443640 0.8754022 11 77354755 77354936 182 + 1.198 1.042 -0.561
ENSMUSG00000020836 E011 8.3883839 0.0036162340 0.813028424 0.9837689 11 77356492 77356614 123 + 0.984 0.949 -0.129
ENSMUSG00000020836 E012 8.7107243 0.0027044635 0.991220017 1.0000000 11 77357021 77357150 130 + 0.984 0.974 -0.035
ENSMUSG00000020836 E013 14.9839359 0.0014108015 0.124008588 0.6746527 11 77357244 77357425 182 + 1.111 1.239 0.453
ENSMUSG00000020836 E014 29.1298724 0.0065683704 0.082789812 0.6035355 11 77357592 77358049 458 + 1.395 1.510 0.393
ENSMUSG00000020836 E015 4.4287390 0.0045780857 0.903130124 0.9956323 11 77358050 77358169 120 + 0.742 0.717 -0.102
ENSMUSG00000020836 E016 26.4418608 0.0127134543 0.913324219 0.9972978 11 77358170 77358575 406 + 1.442 1.420 -0.079
ENSMUSG00000020836 E017 9.4888661 0.0838036204 0.467376417 0.9193982 11 77358576 77358695 120 + 1.067 0.973 -0.348
ENSMUSG00000020836 E018 9.8686410 0.0020045630 0.948363256 1.0000000 11 77358696 77358878 183 + 1.036 1.020 -0.058
ENSMUSG00000020836 E019 10.8603672 0.0018050020 0.826561767 0.9854840 11 77358879 77359091 213 + 1.083 1.052 -0.112
ENSMUSG00000020836 E020 5.7711897 0.0241356673 0.497852471 0.9275663 11 77359092 77359196 105 + 0.880 0.779 -0.394
ENSMUSG00000020836 E021 10.6752546 0.0827793684 0.330960529 0.8626507 11 77359287 77359432 146 + 1.137 0.998 -0.506
ENSMUSG00000020836 E022 8.5485551 0.0024351415 0.688492864 0.9629190 11 77359736 77359793 58 + 1.002 0.949 -0.196
ENSMUSG00000020836 E023 20.2114784 0.0009777402 0.485582124 0.9253847 11 77359883 77360113 231 + 1.290 1.333 0.151
ENSMUSG00000020836 E024 1.9681496 0.0085681285 0.087955985 0.6161936 11 77360202 77360204 3 + 0.261 0.560 1.679
ENSMUSG00000020836 E025 71.3552871 0.0003292843 0.587741970 0.9512445 11 77360205 77361310 1106 + 1.843 1.853 0.034

Help

Please Click HERE to learn more details about the results from DEXseq.