ENSMUSG00000021392

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENSMUST00000021824 ENSMUSG00000021392 Control shVgll3 Nol8 protein_coding protein_coding 3.9844 4.2102 3.7586 0.0161364 0.4040038 -0.1632826 1.3493576 2.0566905 0.6420248 0.13816696 0.32205958 -1.66432366 0.32725000 0.48863333 0.16586667 -0.32276667 6.390109e-01 1.346351e-05 FALSE TRUE
ENSMUST00000221142 ENSMUSG00000021392 Control shVgll3 Nol8 protein_coding protein_coding 3.9844 4.2102 3.7586 0.0161364 0.4040038 -0.1632826 0.5961572 0.0000000 1.1923145 0.00000000 0.32542963 6.90967050 0.16323333 0.00000000 0.32646667 0.32646667 1.346351e-05 1.346351e-05 FALSE TRUE
ENSMUST00000221328 ENSMUSG00000021392 Control shVgll3 Nol8 protein_coding retained_intron 3.9844 4.2102 3.7586 0.0161364 0.4040038 -0.1632826 0.2021590 0.2664144 0.1379035 0.08840063 0.03694677 -0.90217627 0.05128333 0.06326667 0.03930000 -0.02396667 9.706657e-01 1.346351e-05 TRUE TRUE
ENSMUST00000222197 ENSMUSG00000021392 Control shVgll3 Nol8 protein_coding protein_coding 3.9844 4.2102 3.7586 0.0161364 0.4040038 -0.1632826 1.3084618 1.5035971 1.1133264 0.05246281 0.07110170 -0.43020405 0.33133333 0.35706667 0.30560000 -0.05146667 9.706657e-01 1.346351e-05 FALSE TRUE
ENSMUST00000222333 ENSMUSG00000021392 Control shVgll3 Nol8 protein_coding protein_coding 3.9844 4.2102 3.7586 0.0161364 0.4040038 -0.1632826 0.1564681 0.0000000 0.3129361 0.00000000 0.31293614 5.01317700 0.03426667 0.00000000 0.06853333 0.06853333 9.706657e-01 1.346351e-05 FALSE FALSE
ENSMUST00000223346 ENSMUSG00000021392 Control shVgll3 Nol8 protein_coding retained_intron 3.9844 4.2102 3.7586 0.0161364 0.4040038 -0.1632826 0.2600473 0.2526798 0.2674148 0.03879428 0.02669192 0.07873933 0.06605000 0.05996667 0.07213333 0.01216667 9.706657e-01 1.346351e-05   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand shVgll3 Control log2fold_Control_shVgll3
ENSMUSG00000021392 E001 0.0000000       13 49806554 49806555 2 +      
ENSMUSG00000021392 E002 0.3227068 0.3395445149 0.229069472   13 49806556 49806578 23 + 0.234 0.000 -10.508
ENSMUSG00000021392 E003 1.4800299 0.3652051327 0.356757999 0.87517695 13 49806579 49806607 29 + 0.498 0.280 -1.244
ENSMUSG00000021392 E004 4.9272556 0.0039906176 0.927900732 0.99930331 13 49806608 49806808 201 + 0.780 0.765 -0.058
ENSMUSG00000021392 E005 1.6417389 0.0098023557 0.091655419 0.62492226 13 49806809 49806814 6 + 0.235 0.533 1.749
ENSMUSG00000021392 E006 2.1361210 0.0080203351 0.274565542 0.81998154 13 49806815 49806825 11 + 0.387 0.570 0.919
ENSMUSG00000021392 E007 4.4324429 0.0042031359 0.192431559 0.76838742 13 49806826 49806873 48 + 0.626 0.808 0.749
ENSMUSG00000021392 E008 8.3746093 0.0107981170 0.916684990 0.99768646 13 49806874 49807004 131 + 0.966 0.975 0.034
ENSMUSG00000021392 E009 13.0271840 0.0016981807 0.196606725 0.77178036 13 49807005 49807158 154 + 1.206 1.085 -0.434
ENSMUSG00000021392 E010 0.9907071 0.0160591978 0.538772127 0.93662476 13 49807159 49807339 181 + 0.235 0.344 0.750
ENSMUSG00000021392 E011 4.6364004 0.1870268771 0.444207174 0.91335964 13 49807823 49807826 4 + 0.853 0.636 -0.882
ENSMUSG00000021392 E012 16.0022994 0.0063479486 0.030985807 0.39774963 13 49807827 49807978 152 + 1.324 1.126 -0.701
ENSMUSG00000021392 E013 7.0714195 0.0037819556 0.059340713 0.52850008 13 49808649 49808711 63 + 1.014 0.787 -0.864
ENSMUSG00000021392 E014 13.4823982 0.0030531853 0.899938586 0.99563225 13 49810151 49810229 79 + 1.155 1.164 0.032
ENSMUSG00000021392 E015 12.7942187 0.0310164517 0.959158873 1.00000000 13 49812172 49812307 136 + 1.143 1.136 -0.028
ENSMUSG00000021392 E016 10.0182446 0.0215356329 0.639731512 0.95668705 13 49813426 49813494 69 + 1.071 1.015 -0.205
ENSMUSG00000021392 E017 155.6261402 0.0002000064 0.148580259 0.71578801 13 49814434 49816251 1818 + 2.176 2.207 0.105
ENSMUSG00000021392 E018 13.8155999 0.0014181100 0.911627320 0.99710304 13 49817530 49817643 114 + 1.166 1.173 0.025
ENSMUSG00000021392 E019 12.0220932 0.0050440030 0.918854426 0.99768646 13 49818204 49818326 123 + 1.109 1.116 0.027
ENSMUSG00000021392 E020 14.1824984 0.0026646604 0.336651043 0.86669971 13 49818855 49818945 91 + 1.225 1.136 -0.318
ENSMUSG00000021392 E021 0.8214557 0.0174300726 0.795869106 0.98100799 13 49819993 49820830 838 + 0.235 0.280 0.334
ENSMUSG00000021392 E022 19.7988291 0.0063911504 0.519339527 0.93163045 13 49820831 49820966 136 + 1.346 1.288 -0.203
ENSMUSG00000021392 E023 16.5975582 0.0197237776 0.204316971 0.77896936 13 49820967 49823177 2211 + 1.309 1.181 -0.454
ENSMUSG00000021392 E024 0.4940258 0.0226272693 0.668076675   13 49823178 49823184 7 + 0.133 0.205 0.749
ENSMUSG00000021392 E025 8.2266992 0.0024269889 0.796868282 0.98108073 13 49823185 49823262 78 + 0.949 0.975 0.097
ENSMUSG00000021392 E026 31.9362246 0.0079446726 0.916007038 0.99768646 13 49826028 49826299 272 + 1.513 1.518 0.017
ENSMUSG00000021392 E027 21.0908374 0.0016255145 0.904955842 0.99563225 13 49828862 49828988 127 + 1.339 1.345 0.020
ENSMUSG00000021392 E028 3.9522650 0.0195697349 0.246037825 0.80442163 13 49828989 49829797 809 + 0.588 0.766 0.750
ENSMUSG00000021392 E029 14.4890839 0.0026270818 0.002173009 0.08307142 13 49829798 49829865 68 + 1.014 1.295 1.003
ENSMUSG00000021392 E030 1.1572930 0.0130901015 0.078495244 0.59153254 13 49829866 49830230 365 + 0.133 0.449 2.334
ENSMUSG00000021392 E031 15.4321651 0.0135181806 0.482399406 0.92372810 13 49830231 49830310 80 + 1.176 1.245 0.245
ENSMUSG00000021392 E032 57.9289548 0.0003938136 0.460093014 0.91682762 13 49831862 49832492 631 + 1.787 1.752 -0.120

Help

Please Click HERE to learn more details about the results from DEXseq.