ENSMUSG00000024050

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENSMUST00000087703 ENSMUSG00000024050 Control shVgll3 Wiz protein_coding protein_coding 16.14118 15.57937 16.70299 0.1972338 0.5532292 0.1004075 1.3039529 1.384498 1.2234074 0.42471071 0.07845921 -0.17709667 0.08136667 0.08960000 0.073133333 -0.01646667 9.914345e-01 8.010936e-05 FALSE  
ENSMUST00000163107 ENSMUSG00000024050 Control shVgll3 Wiz protein_coding nonsense_mediated_decay 16.14118 15.57937 16.70299 0.1972338 0.5532292 0.1004075 0.7047234 1.239097 0.1703502 0.12992270 0.09840209 -2.79201220 0.04471667 0.07956667 0.009866667 -0.06970000 8.010936e-05 8.010936e-05 FALSE  
MSTRG.9944.1 ENSMUSG00000024050 Control shVgll3 Wiz protein_coding   16.14118 15.57937 16.70299 0.1972338 0.5532292 0.1004075 5.7447905 5.630165 5.8594157 0.69008584 0.73074336 0.05747943 0.35500000 0.36040000 0.349600000 -0.01080000 1.000000e+00 8.010936e-05 FALSE  
MSTRG.9944.4 ENSMUSG00000024050 Control shVgll3 Wiz protein_coding   16.14118 15.57937 16.70299 0.1972338 0.5532292 0.1004075 4.3006965 3.337806 5.2635866 0.68716788 0.49669078 0.65556844 0.26585000 0.21540000 0.316300000 0.10090000 8.906711e-01 8.010936e-05 FALSE  
MSTRG.9944.6 ENSMUSG00000024050 Control shVgll3 Wiz protein_coding   16.14118 15.57937 16.70299 0.1972338 0.5532292 0.1004075 2.0445137 1.821708 2.2673190 0.08478083 0.03250126 0.31414657 0.12658333 0.11706667 0.136100000 0.01903333 9.706657e-01 8.010936e-05 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand shVgll3 Control log2fold_Control_shVgll3
ENSMUSG00000024050 E001 0.8266786 0.0167549696 0.589230300 0.95124454 17 32572991 32573028 38 - 0.212 0.308 0.709
ENSMUSG00000024050 E002 0.8266786 0.0167549696 0.589230300 0.95124454 17 32573029 32573030 2 - 0.212 0.308 0.709
ENSMUSG00000024050 E003 0.8266786 0.0167549696 0.589230300 0.95124454 17 32573031 32573034 4 - 0.212 0.308 0.709
ENSMUSG00000024050 E004 0.8312189 0.0173772822 0.729506273 0.97107356 17 32573035 32573045 11 - 0.289 0.227 -0.461
ENSMUSG00000024050 E005 310.6237977 0.0004399726 0.844789430 0.98686918 17 32573046 32573622 577 - 2.496 2.491 -0.018
ENSMUSG00000024050 E006 244.3377931 0.0001446267 0.080925722 0.59915766 17 32573623 32573997 375 - 2.371 2.408 0.122
ENSMUSG00000024050 E007 110.5583609 0.0002042359 0.645347799 0.95668705 17 32573998 32574157 160 - 2.040 2.054 0.047
ENSMUSG00000024050 E008 89.9480048 0.0002768300 0.709031159 0.96617147 17 32575397 32575592 196 - 1.966 1.951 -0.050
ENSMUSG00000024050 E009 163.7661776 0.0002259298 0.459835725 0.91682762 17 32575863 32576282 420 - 2.207 2.226 0.063
ENSMUSG00000024050 E010 217.0333978 0.0002350957 0.767788926 0.97799068 17 32576431 32576955 525 - 2.342 2.334 -0.027
ENSMUSG00000024050 E011 10.8637358 0.0017034388 0.550067832 0.93707028 17 32576956 32576958 3 - 1.045 1.103 0.212
ENSMUSG00000024050 E012 232.7107333 0.0001639635 0.952198660 1.00000000 17 32577917 32578468 552 - 2.370 2.367 -0.009
ENSMUSG00000024050 E013 39.8082650 0.0004763752 0.554491290 0.93888081 17 32578469 32579011 543 - 1.626 1.593 -0.115
ENSMUSG00000024050 E014 87.9209186 0.0033818156 0.027545418 0.37337925 17 32579012 32579401 390 - 1.995 1.892 -0.345
ENSMUSG00000024050 E015 55.4639540 0.0016653247 0.040388796 0.45152905 17 32579402 32580434 1033 - 1.798 1.694 -0.351
ENSMUSG00000024050 E016 159.9175820 0.0002620637 0.676935243 0.96164256 17 32580435 32580787 353 - 2.212 2.200 -0.042
ENSMUSG00000024050 E017 32.1070622 0.0007114614 0.309269130 0.84799771 17 32580788 32580882 95 - 1.549 1.485 -0.218
ENSMUSG00000024050 E018 24.4751858 0.0025722088 0.151640512 0.71966970 17 32580883 32580938 56 - 1.454 1.348 -0.365
ENSMUSG00000024050 E019 33.2549554 0.0008391286 0.006622392 0.17292130 17 32581767 32581937 171 - 1.606 1.439 -0.575
ENSMUSG00000024050 E020 26.0173195 0.0069881653 0.150534401 0.71778715 17 32583156 32583488 333 - 1.482 1.368 -0.393
ENSMUSG00000024050 E021 18.4724464 0.0516086974 0.468408167 0.91939825 17 32586005 32586797 793 - 1.241 1.335 0.332
ENSMUSG00000024050 E022 28.2880521 0.0007134295 0.001679375 0.07122958 17 32586798 32587044 247 - 1.357 1.561 0.702
ENSMUSG00000024050 E023 15.2854936 0.0027643624 0.003401071 0.11164849 17 32587045 32587121 77 - 1.069 1.328 0.919
ENSMUSG00000024050 E024 0.6594496 0.0345052721 0.930104753   17 32588261 32588278 18 - 0.212 0.227 0.124
ENSMUSG00000024050 E025 0.4889862 0.0217068710 0.619935925   17 32588279 32588394 116 - 0.212 0.128 -0.876
ENSMUSG00000024050 E026 0.1613534 0.0343589473 0.527205319   17 32588395 32588426 32 - 0.119 0.000 -11.302
ENSMUSG00000024050 E027 0.3334988 0.3230465763 0.300785369   17 32595152 32595489 338 - 0.213 0.000 -11.292
ENSMUSG00000024050 E028 0.3334988 0.3230465763 0.300785369   17 32595490 32595496 7 - 0.213 0.000 -11.292
ENSMUSG00000024050 E029 19.7186733 0.0314846890 0.659287774 0.95774869 17 32595497 32596867 1371 - 1.338 1.291 -0.165
ENSMUSG00000024050 E030 5.7416786 0.0582112431 0.689653629 0.96291900 17 32596868 32597472 605 - 0.863 0.789 -0.287
ENSMUSG00000024050 E031 8.2426290 0.0096840057 0.281359826 0.82724503 17 32597814 32598092 279 - 0.900 1.026 0.473
ENSMUSG00000024050 E032 0.8301897 0.1186068377 0.181211045 0.76033243 17 32600030 32600057 28 - 0.119 0.376 2.125
ENSMUSG00000024050 E033 6.5777381 0.0027975228 0.013332823 0.25319377 17 32600058 32600130 73 - 0.707 1.012 1.178
ENSMUSG00000024050 E034 23.3555139 0.0011110238 0.030089179 0.39123545 17 32606547 32606791 245 - 1.306 1.460 0.533
ENSMUSG00000024050 E035 0.4982597 0.6010832755 0.292842148   17 32607413 32607577 165 - 0.290 0.000 -11.640
ENSMUSG00000024050 E036 5.2798209 0.0060388360 0.655752888 0.95668705 17 32607578 32607729 152 - 0.824 0.764 -0.239
ENSMUSG00000024050 E037 3.2994638 0.1421678627 0.987736345 1.00000000 17 32607730 32607791 62 - 0.619 0.647 0.122
ENSMUSG00000024050 E038 7.2382073 0.0024763219 0.237622588 0.80442163 17 32607792 32608090 299 - 0.844 0.982 0.520
ENSMUSG00000024050 E039 4.2921627 0.1012101288 0.035787556 0.42724341 17 32608234 32608413 180 - 0.461 0.897 1.862

Help

Please Click HERE to learn more details about the results from DEXseq.