ENSMUSG00000024188

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENSMUST00000025023 ENSMUSG00000024188 Control shVgll3 Luc7l protein_coding protein_coding 35.6601 32.09626 39.22394 0.3563543 0.8019357 0.2892473 11.181932 10.853691 11.510173 1.3140678 1.4859030 0.0846481 0.3162000 0.33876667 0.29363333 -0.04513333 0.9706657 0.0112329 FALSE TRUE
ENSMUST00000133032 ENSMUSG00000024188 Control shVgll3 Luc7l protein_coding retained_intron 35.6601 32.09626 39.22394 0.3563543 0.8019357 0.2892473 15.229886 11.908966 18.550807 0.4499999 0.6634121 0.6390003 0.4218333 0.37090000 0.47276667 0.10186667 0.0112329 0.0112329 FALSE TRUE
ENSMUST00000155151 ENSMUSG00000024188 Control shVgll3 Luc7l protein_coding protein_coding_CDS_not_defined 35.6601 32.09626 39.22394 0.3563543 0.8019357 0.2892473 2.022255 1.474718 2.569793 0.8169609 0.5915635 0.7970666 0.0556000 0.04553333 0.06566667 0.02013333 0.9706657 0.0112329 TRUE FALSE
MSTRG.9808.2 ENSMUSG00000024188 Control shVgll3 Luc7l protein_coding   35.6601 32.09626 39.22394 0.3563543 0.8019357 0.2892473 5.534535 5.851895 5.217175 0.1607365 0.2407899 -0.1653356 0.1576333 0.18236667 0.13290000 -0.04946667 0.1056905 0.0112329 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand shVgll3 Control log2fold_Control_shVgll3
ENSMUSG00000024188 E001 0.000000       17 26471870 26471907 38 +      
ENSMUSG00000024188 E002 5.597072 0.0032770836 6.464143e-01 9.566871e-01 17 26471908 26471924 17 + 0.790 0.849 0.229
ENSMUSG00000024188 E003 7.069530 0.0026484592 7.141066e-01 9.684148e-01 17 26471925 26471929 5 + 0.886 0.928 0.162
ENSMUSG00000024188 E004 13.985941 0.0074941571 3.298793e-01 8.624124e-01 17 26471930 26471939 10 + 1.129 1.222 0.331
ENSMUSG00000024188 E005 28.830358 0.0006538538 9.383117e-01 9.996345e-01 17 26471940 26471957 18 + 1.475 1.470 -0.019
ENSMUSG00000024188 E006 42.318309 0.0005053406 2.521155e-01 8.064662e-01 17 26471958 26471972 15 + 1.663 1.600 -0.213
ENSMUSG00000024188 E007 92.428206 0.0002898198 3.510955e-01 8.751770e-01 17 26471973 26472065 93 + 1.984 1.949 -0.118
ENSMUSG00000024188 E008 48.319829 0.0061751781 5.013493e-01 9.278351e-01 17 26472066 26472195 130 + 1.671 1.713 0.140
ENSMUSG00000024188 E009 120.571362 0.0004672328 9.035346e-01 9.956323e-01 17 26472196 26472653 458 + 2.082 2.085 0.012
ENSMUSG00000024188 E010 109.331211 0.0025270889 9.072427e-01 9.956590e-01 17 26472654 26472947 294 + 2.044 2.038 -0.019
ENSMUSG00000024188 E011 95.588567 0.0002357149 7.702240e-02 5.886750e-01 17 26472948 26473018 71 + 2.012 1.948 -0.217
ENSMUSG00000024188 E012 312.807293 0.0002735546 4.310703e-03 1.295080e-01 17 26473019 26473362 344 + 2.521 2.462 -0.197
ENSMUSG00000024188 E013 273.940096 0.0001751013 8.696982e-03 2.029247e-01 17 26473363 26474004 642 + 2.463 2.406 -0.188
ENSMUSG00000024188 E014 96.744437 0.0013504569 8.473391e-01 9.868692e-01 17 26474005 26474099 95 + 1.992 1.984 -0.027
ENSMUSG00000024188 E015 108.007216 0.0001991831 5.943070e-01 9.516577e-01 17 26476900 26476998 99 + 2.044 2.026 -0.063
ENSMUSG00000024188 E016 118.721030 0.0029553416 5.329040e-01 9.365485e-01 17 26485257 26485367 111 + 2.065 2.089 0.081
ENSMUSG00000024188 E017 58.217244 0.0139273857 4.724274e-01 9.212295e-01 17 26486189 26486248 60 + 1.793 1.742 -0.174
ENSMUSG00000024188 E018 83.347118 0.0035499428 8.875518e-01 9.945296e-01 17 26486249 26486332 84 + 1.927 1.921 -0.022
ENSMUSG00000024188 E019 209.860766 0.0008487237 3.178281e-01 8.535245e-01 17 26494648 26494824 177 + 2.335 2.307 -0.092
ENSMUSG00000024188 E020 151.916770 0.0016790598 3.771733e-01 8.796144e-01 17 26496520 26496608 89 + 2.197 2.166 -0.101
ENSMUSG00000024188 E021 62.840894 0.0042506714 9.392364e-01 9.996345e-01 17 26498307 26498336 30 + 1.806 1.802 -0.014
ENSMUSG00000024188 E022 136.684809 0.0002243702 2.226708e-01 7.980380e-01 17 26498935 26499102 168 + 2.121 2.157 0.121
ENSMUSG00000024188 E023 36.837792 0.0005326450 3.487095e-01 8.750804e-01 17 26499103 26499138 36 + 1.601 1.546 -0.186
ENSMUSG00000024188 E024 397.156176 0.0004104835 8.979644e-03 2.047639e-01 17 26499139 26499697 559 + 2.621 2.571 -0.166
ENSMUSG00000024188 E025 500.796309 0.0001525279 1.958839e-20 1.636750e-17 17 26500599 26504478 3880 + 2.628 2.770 0.470

Help

Please Click HERE to learn more details about the results from DEXseq.