ENSMUSG00000024381

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENSMUST00000091967 ENSMUSG00000024381 Control shVgll3 Bin1 protein_coding protein_coding 27.50717 28.01588 26.99846 0.7801609 0.7003824 -0.05334799 1.778222 0.967742 2.588701 0.6078854 0.7749704 1.4102650 0.06663333 0.03576667 0.0975000 0.06173333 0.9706656688 0.0009369405 FALSE TRUE
ENSMUST00000234496 ENSMUSG00000024381 Control shVgll3 Bin1 protein_coding protein_coding 27.50717 28.01588 26.99846 0.7801609 0.7003824 -0.05334799 14.951222 18.167141 11.735303 0.9915478 0.1936062 -0.6300414 0.54203333 0.64863333 0.4354333 -0.21320000 0.0009369405 0.0009369405 FALSE TRUE
ENSMUST00000234857 ENSMUSG00000024381 Control shVgll3 Bin1 protein_coding protein_coding 27.50717 28.01588 26.99846 0.7801609 0.7003824 -0.05334799 4.543043 3.553692 5.532394 1.4553224 1.4686280 0.6371368 0.16366667 0.12483333 0.2025000 0.07766667 0.9706656688 0.0009369405 FALSE TRUE
MSTRG.10878.1 ENSMUSG00000024381 Control shVgll3 Bin1 protein_coding   27.50717 28.01588 26.99846 0.7801609 0.7003824 -0.05334799 2.090327 1.771065 2.409589 0.1558730 0.1519810 0.4420217 0.07643333 0.06356667 0.0893000 0.02573333 0.6333850502 0.0009369405 FALSE TRUE
MSTRG.10878.2 ENSMUSG00000024381 Control shVgll3 Bin1 protein_coding   27.50717 28.01588 26.99846 0.7801609 0.7003824 -0.05334799 3.179446 2.563649 3.795243 0.1012261 0.1280822 0.5641733 0.11641667 0.09183333 0.1410000 0.04916667 0.1802935412 0.0009369405 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand shVgll3 Control log2fold_Control_shVgll3
ENSMUSG00000024381 E001 0.5002482 0.6020354416 2.962359e-01   18 32510127 32510274 148 + 0.290 0.000 -10.751
ENSMUSG00000024381 E002 0.0000000       18 32510275 32510282 8 +      
ENSMUSG00000024381 E003 0.0000000       18 32510283 32510297 15 +      
ENSMUSG00000024381 E004 0.0000000       18 32510298 32510309 12 +      
ENSMUSG00000024381 E005 0.0000000       18 32510310 32510543 234 +      
ENSMUSG00000024381 E006 51.9857380 0.0003762521 6.365091e-01 9.566871e-01 18 32539153 32539233 81 + 1.736 1.710 -0.089
ENSMUSG00000024381 E007 0.0000000       18 32540687 32540806 120 +      
ENSMUSG00000024381 E008 49.5379845 0.0026107382 4.907345e-02 4.868652e-01 18 32545474 32545528 55 + 1.651 1.754 0.351
ENSMUSG00000024381 E009 73.3272625 0.0002898316 9.981967e-01 1.000000e+00 18 32545670 32545764 95 + 1.873 1.869 -0.012
ENSMUSG00000024381 E010 65.7299553 0.0024425798 3.921156e-01 8.872502e-01 18 32546148 32546243 96 + 1.805 1.844 0.130
ENSMUSG00000024381 E011 77.1990598 0.0005638772 6.495701e-01 9.566871e-01 18 32547236 32547343 108 + 1.885 1.900 0.050
ENSMUSG00000024381 E012 0.1615462 0.0344969095 4.446447e-01   18 32547998 32548090 93 + 0.000 0.128 12.077
ENSMUSG00000024381 E013 63.3608007 0.0005577316 9.970593e-01 1.000000e+00 18 32552896 32552981 86 + 1.810 1.806 -0.012
ENSMUSG00000024381 E014 75.6760522 0.0012362322 2.464620e-01 8.044216e-01 18 32553122 32553197 76 + 1.862 1.908 0.155
ENSMUSG00000024381 E015 107.8170338 0.0002214901 8.968990e-02 6.193580e-01 18 32554931 32555013 83 + 2.010 2.063 0.179
ENSMUSG00000024381 E016 132.6272255 0.0002195382 5.772188e-01 9.467619e-01 18 32557873 32558020 148 + 2.119 2.132 0.045
ENSMUSG00000024381 E017 41.0563140 0.0107643092 2.777073e-02 3.753378e-01 18 32559277 32559405 129 + 1.694 1.528 -0.567
ENSMUSG00000024381 E018 107.4189428 0.0032383461 5.408637e-02 5.094222e-01 18 32559406 32560739 1334 + 2.073 1.987 -0.288
ENSMUSG00000024381 E019 23.9517223 0.0120166937 2.132382e-01 7.859620e-01 18 32560740 32561086 347 + 1.448 1.335 -0.388
ENSMUSG00000024381 E020 112.6296841 0.0002568265 4.575445e-04 2.681924e-02 18 32561087 32562248 1162 + 2.108 1.989 -0.402
ENSMUSG00000024381 E021 17.7775489 0.0010821366 1.813299e-02 3.043324e-01 18 32562249 32562356 108 + 1.356 1.159 -0.693
ENSMUSG00000024381 E022 45.8092513 0.0100602179 2.733609e-02 3.718344e-01 18 32562357 32562752 396 + 1.738 1.581 -0.533
ENSMUSG00000024381 E023 7.0690157 0.0030797957 8.681136e-01 9.889212e-01 18 32562753 32562776 24 + 0.899 0.915 0.063
ENSMUSG00000024381 E024 137.1811987 0.0026184571 1.757538e-03 7.239322e-02 18 32562777 32563802 1026 + 2.194 2.072 -0.408
ENSMUSG00000024381 E025 17.5645648 0.0045753755 3.787896e-01 8.800006e-01 18 32563803 32563910 108 + 1.305 1.226 -0.277
ENSMUSG00000024381 E026 21.2375848 0.0183700459 2.022330e-01 7.768696e-01 18 32563911 32564044 134 + 1.402 1.276 -0.437
ENSMUSG00000024381 E027 75.5856392 0.0003346276 4.843703e-02 4.839731e-01 18 32564045 32564723 679 + 1.921 1.838 -0.281
ENSMUSG00000024381 E028 33.5769900 0.0006851091 2.649148e-02 3.641567e-01 18 32564724 32564795 72 + 1.599 1.461 -0.472
ENSMUSG00000024381 E029 42.1419452 0.0004684634 5.091851e-02 4.944225e-01 18 32564796 32565035 240 + 1.683 1.574 -0.370
ENSMUSG00000024381 E030 122.4826195 0.0002469013 2.030811e-01 7.776243e-01 18 32565036 32565146 111 + 2.073 2.110 0.123
ENSMUSG00000024381 E031 122.2871864 0.0002032349 7.221674e-01 9.706108e-01 18 32565377 32565478 102 + 2.087 2.094 0.026
ENSMUSG00000024381 E032 512.8652306 0.0001954605 1.793232e-11 6.766848e-09 18 32568188 32568790 603 + 2.663 2.757 0.314

Help

Please Click HERE to learn more details about the results from DEXseq.