ENSMUSG00000024910

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENSMUST00000235502 ENSMUSG00000024910 Control shVgll3 Ctsw protein_coding retained_intron 0.4950743 0.3548486 0.6352999 0.09739994 0.1208021 0.822672 0.11748032 0.12644708 0.10851356 0.06365383 0.02125874 -0.2032894 0.35356667 0.5132000 0.1939333 -0.31926667 0.970665669 0.000260227 TRUE TRUE
ENSMUST00000235786 ENSMUSG00000024910 Control shVgll3 Ctsw protein_coding retained_intron 0.4950743 0.3548486 0.6352999 0.09739994 0.1208021 0.822672 0.06257875 0.05759478 0.06756273 0.05759478 0.01678486 0.1984516 0.12863333 0.1534667 0.1038000 -0.04966667 1.000000000 0.000260227 TRUE TRUE
ENSMUST00000236091 ENSMUSG00000024910 Control shVgll3 Ctsw protein_coding retained_intron 0.4950743 0.3548486 0.6352999 0.09739994 0.1208021 0.822672 0.22961183 0.00000000 0.45922365 0.00000000 0.11723313 5.5522038 0.35113333 0.0000000 0.7022667 0.70226667 0.000260227 0.000260227 TRUE FALSE
ENSMUST00000236256 ENSMUSG00000024910 Control shVgll3 Ctsw protein_coding protein_coding 0.4950743 0.3548486 0.6352999 0.09739994 0.1208021 0.822672 0.05228394 0.10456787 0.00000000 0.10456787 0.00000000 -3.5181306 0.10203333 0.2040667 0.0000000 -0.20406667 0.970665669 0.000260227 FALSE TRUE
ENSMUST00000237556 ENSMUSG00000024910 Control shVgll3 Ctsw protein_coding retained_intron 0.4950743 0.3548486 0.6352999 0.09739994 0.1208021 0.822672 0.03311942 0.06623884 0.00000000 0.06623884 0.00000000 -2.9305262 0.06463333 0.1292667 0.0000000 -0.12926667 0.970665669 0.000260227   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand shVgll3 Control log2fold_Control_shVgll3
ENSMUSG00000024910 E001 1.3102592 0.014378904 0.0745776225 0.58325131 19 5515071 5515267 197 - 0.513 0.198 -1.969
ENSMUSG00000024910 E002 0.4975470 0.291010185 0.7086897785   19 5515268 5515270 3 - 0.139 0.198 0.617
ENSMUSG00000024910 E003 1.9653708 0.009424519 0.3922253477 0.88725021 19 5515271 5515479 209 - 0.399 0.519 0.616
ENSMUSG00000024910 E004 0.8301897 0.473573788 0.3825223070 0.88319542 19 5515558 5515665 108 - 0.139 0.334 1.618
ENSMUSG00000024910 E005 0.4888227 0.024687909 0.1211316588   19 5515666 5515735 70 - 0.000 0.270 12.947
ENSMUSG00000024910 E006 0.4889958 0.025432531 0.1209359026   19 5515736 5515758 23 - 0.000 0.270 12.947
ENSMUSG00000024910 E007 1.1478962 0.014063139 0.3596751849 0.87517695 19 5515833 5515897 65 - 0.243 0.387 0.938
ENSMUSG00000024910 E008 1.1522533 0.017041135 0.3550553758 0.87517695 19 5516048 5516138 91 - 0.243 0.387 0.938
ENSMUSG00000024910 E009 0.3274400 0.029045271 0.1508441397   19 5516139 5516173 35 - 0.243 0.000 -13.128
ENSMUSG00000024910 E010 1.3259478 0.017203234 0.0004909515 0.02811961 19 5516174 5516258 85 - 0.603 0.000 -15.129
ENSMUSG00000024910 E011 0.9924586 0.017978119 0.2801118062 0.82531292 19 5516259 5516339 81 - 0.399 0.198 -1.385
ENSMUSG00000024910 E012 0.3274496 0.029919219 0.2633065768   19 5516340 5516416 77 - 0.000 0.198 12.362
ENSMUSG00000024910 E013 0.4888030 0.025437882 0.6980572141   19 5516417 5516513 97 - 0.139 0.198 0.616
ENSMUSG00000024910 E014 0.8117223 0.019802534 0.2458565550 0.80442163 19 5516609 5516695 87 - 0.139 0.333 1.616
ENSMUSG00000024910 E015 0.4889862 0.023768184 0.4513109003   19 5516696 5516763 68 - 0.243 0.110 -1.384
ENSMUSG00000024910 E016 1.1494549 0.014667907 0.1452242045 0.71005403 19 5516764 5517050 287 - 0.459 0.198 -1.706
ENSMUSG00000024910 E017 0.4891790 0.026362984 0.7027525746   19 5517051 5517164 114 - 0.139 0.198 0.615
ENSMUSG00000024910 E018 0.1657302 0.046518830 0.5840721941   19 5517866 5517950 85 - 0.000 0.110 11.363
ENSMUSG00000024910 E019 0.1615462 0.036116329 0.5875168479   19 5518431 5518535 105 - 0.000 0.110 11.362

Help

Please Click HERE to learn more details about the results from DEXseq.