ENSMUSG00000026074

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENSMUST00000191657 ENSMUSG00000026074 Control shVgll3 Map4k4 protein_coding retained_intron 28.46987 30.20994 26.7298 1.504653 1.253225 -0.1765125 2.7058179 3.308775 2.102861 0.9166819 0.7994417 -0.65145299 0.09295000 0.10863333 0.07726667 -0.03136667 9.706657e-01 6.464896e-12    
ENSMUST00000192884 ENSMUSG00000026074 Control shVgll3 Map4k4 protein_coding retained_intron 28.46987 30.20994 26.7298 1.504653 1.253225 -0.1765125 3.4974861 3.616942 3.378030 1.1483777 0.4024463 -0.09830717 0.12205000 0.11790000 0.12620000 0.00830000 9.857477e-01 6.464896e-12 FALSE  
ENSMUST00000193682 ENSMUSG00000026074 Control shVgll3 Map4k4 protein_coding protein_coding 28.46987 30.20994 26.7298 1.504653 1.253225 -0.1765125 6.0936699 6.890415 5.296925 0.4083244 0.6444146 -0.37880681 0.21261667 0.22840000 0.19683333 -0.03156667 9.706657e-01 6.464896e-12 FALSE  
MSTRG.293.2 ENSMUSG00000026074 Control shVgll3 Map4k4 protein_coding   28.46987 30.20994 26.7298 1.504653 1.253225 -0.1765125 0.9166431 1.833286 0.000000 0.2354295 0.0000000 -7.52613632 0.03085000 0.06170000 0.00000000 -0.06170000 6.464896e-12 6.464896e-12 FALSE  
MSTRG.293.25 ENSMUSG00000026074 Control shVgll3 Map4k4 protein_coding   28.46987 30.20994 26.7298 1.504653 1.253225 -0.1765125 3.7897876 2.979421 4.600154 1.5532286 0.4543354 0.62494902 0.13841667 0.10316667 0.17366667 0.07050000 9.706657e-01 6.464896e-12 FALSE  
MSTRG.293.4 ENSMUSG00000026074 Control shVgll3 Map4k4 protein_coding   28.46987 30.20994 26.7298 1.504653 1.253225 -0.1765125 2.0589640 2.487624 1.630304 0.2430829 0.6254914 -0.60659359 0.07276667 0.08353333 0.06200000 -0.02153333 9.706657e-01 6.464896e-12 FALSE  
MSTRG.293.6 ENSMUSG00000026074 Control shVgll3 Map4k4 protein_coding   28.46987 30.20994 26.7298 1.504653 1.253225 -0.1765125 4.6351560 3.994748 5.275564 0.1447004 0.6132147 0.40034612 0.16535000 0.13336667 0.19733333 0.06396667 5.875454e-01 6.464896e-12 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand shVgll3 Control log2fold_Control_shVgll3
ENSMUSG00000026074 E001 0.3274400 0.0258174490 0.176513227   1 39939955 39939968 14 + 0.227 0.000 -11.097
ENSMUSG00000026074 E002 0.4933433 0.0217200914 0.516634647   1 39939969 39940000 32 + 0.227 0.119 -1.122
ENSMUSG00000026074 E003 2.8103144 0.0067185999 0.673111800 0.96145567 1 39940001 39940072 72 + 0.612 0.547 -0.292
ENSMUSG00000026074 E004 46.0819421 0.0004116236 0.327316541 0.86191919 1 39940073 39940329 257 + 1.697 1.649 -0.163
ENSMUSG00000026074 E005 14.3021100 0.0013306529 0.074639017 0.58325131 1 39940330 39940338 9 + 1.259 1.103 -0.556
ENSMUSG00000026074 E006 10.2020816 0.0018506304 0.177948908 0.75677617 1 39940339 39940339 1 + 1.114 0.979 -0.496
ENSMUSG00000026074 E007 21.0269181 0.0009377818 0.618890825 0.95514198 1 39940340 39940383 44 + 1.361 1.326 -0.122
ENSMUSG00000026074 E008 13.4500281 0.0062339374 0.799360848 0.98165184 1 39940384 39940389 6 + 1.147 1.173 0.090
ENSMUSG00000026074 E009 32.3624425 0.0242715956 0.884367300 0.99316692 1 39940390 39940446 57 + 1.512 1.533 0.070
ENSMUSG00000026074 E010 0.4975369 0.0254430845 0.099013474   1 39940638 39940668 31 + 0.000 0.289 13.406
ENSMUSG00000026074 E011 32.5384717 0.0157445392 0.709612703 0.96623901 1 39940669 39940734 66 + 1.539 1.512 -0.092
ENSMUSG00000026074 E012 0.9924490 0.0644679985 0.008318685 0.19801989 1 39940735 39941616 882 + 0.486 0.000 -14.883
ENSMUSG00000026074 E013 31.5735556 0.0005911477 0.965468578 1.00000000 1 40001338 40001394 57 + 1.513 1.512 -0.001
ENSMUSG00000026074 E014 0.0000000       1 40003315 40003364 50 +      
ENSMUSG00000026074 E015 0.0000000       1 40004010 40004061 52 +      
ENSMUSG00000026074 E016 62.2364424 0.0050806861 0.910987836 0.99688828 1 40013087 40013212 126 + 1.805 1.798 -0.022
ENSMUSG00000026074 E017 64.3429573 0.0003467937 0.668521509 0.95961628 1 40015867 40015977 111 + 1.823 1.807 -0.055
ENSMUSG00000026074 E018 66.8382107 0.0069276655 0.513438309 0.93119401 1 40019720 40019810 91 + 1.849 1.813 -0.121
ENSMUSG00000026074 E019 76.2637455 0.0006831099 0.747139028 0.97380952 1 40022299 40022429 131 + 1.880 1.895 0.052
ENSMUSG00000026074 E020 42.9071221 0.0004978721 0.935840246 0.99963445 1 40023043 40023097 55 + 1.639 1.646 0.022
ENSMUSG00000026074 E021 46.5681660 0.0027891984 0.928422618 0.99930331 1 40024342 40024420 79 + 1.678 1.676 -0.009
ENSMUSG00000026074 E022 98.3691396 0.0002084746 0.151648642 0.71966970 1 40025785 40025960 176 + 1.968 2.022 0.178
ENSMUSG00000026074 E023 40.9518451 0.0043307029 0.338305453 0.86768191 1 40028130 40028202 73 + 1.588 1.652 0.216
ENSMUSG00000026074 E024 101.2356576 0.0010526327 0.641801257 0.95668705 1 40029249 40029459 211 + 1.999 2.019 0.066
ENSMUSG00000026074 E025 76.4508682 0.0002744291 0.164815994 0.73847466 1 40036181 40036342 162 + 1.858 1.916 0.196
ENSMUSG00000026074 E026 0.3321731 0.2923420199 0.239755411   1 40038755 40038853 99 + 0.227 0.000 -12.535
ENSMUSG00000026074 E027 1.6432778 0.0096594145 0.444185227 0.91335964 1 40038854 40039047 194 + 0.486 0.354 -0.707
ENSMUSG00000026074 E028 12.8011881 0.0075907572 0.446133201 0.91335964 1 40039048 40039052 5 + 1.178 1.103 -0.269
ENSMUSG00000026074 E029 12.1421145 0.0079495913 0.444375572 0.91335964 1 40039053 40039053 1 + 1.158 1.081 -0.277
ENSMUSG00000026074 E030 40.4237376 0.0006235267 0.754002272 0.97611650 1 40039054 40039134 81 + 1.607 1.627 0.066
ENSMUSG00000026074 E031 27.6283773 0.0006749944 0.623403570 0.95514198 1 40039691 40039783 93 + 1.438 1.473 0.119
ENSMUSG00000026074 E032 44.0361911 0.0055701036 0.622376194 0.95514198 1 40039784 40039836 53 + 1.669 1.639 -0.100
ENSMUSG00000026074 E033 48.3751701 0.0008010832 0.698624323 0.96475394 1 40039837 40039909 73 + 1.681 1.704 0.075
ENSMUSG00000026074 E034 2.8055615 0.0507712555 0.406606256 0.89390915 1 40040590 40040621 32 + 0.647 0.507 -0.635
ENSMUSG00000026074 E035 5.5846729 0.0505000930 0.736127522 0.97290014 1 40040622 40040751 130 + 0.789 0.844 0.218
ENSMUSG00000026074 E036 3.6378984 0.0393875793 0.570844381 0.94387267 1 40042917 40042922 6 + 0.710 0.619 -0.386
ENSMUSG00000026074 E037 43.9623272 0.0004477951 0.006505330 0.17062634 1 40042923 40043147 225 + 1.720 1.579 -0.480
ENSMUSG00000026074 E038 63.8533294 0.0003314028 0.001010931 0.04886726 1 40043967 40044073 107 + 1.880 1.737 -0.481
ENSMUSG00000026074 E039 9.8744936 0.0445788935 0.225623320 0.79846985 1 40045831 40045833 3 + 1.115 0.949 -0.608
ENSMUSG00000026074 E040 61.2750241 0.0055480472 0.784055309 0.97903220 1 40045834 40045982 149 + 1.800 1.787 -0.045
ENSMUSG00000026074 E041 0.0000000       1 40046553 40046592 40 +      
ENSMUSG00000026074 E042 58.7534071 0.0023155579 0.670176075 0.96031857 1 40046593 40046690 98 + 1.763 1.787 0.080
ENSMUSG00000026074 E043 0.3319899 0.0278362370 0.947561957   1 40046691 40046699 9 + 0.128 0.119 -0.122
ENSMUSG00000026074 E044 30.4981720 0.0238882204 0.815081582 0.98399344 1 40046700 40047490 791 + 1.484 1.512 0.095
ENSMUSG00000026074 E045 20.5510779 0.0012817894 0.564047310 0.94217180 1 40047491 40047499 9 + 1.355 1.313 -0.145
ENSMUSG00000026074 E046 10.0377494 0.0018141063 0.590532430 0.95139970 1 40047500 40048489 990 + 1.011 1.069 0.211
ENSMUSG00000026074 E047 97.1421001 0.0027412353 0.618590889 0.95514198 1 40048848 40049023 176 + 2.002 1.982 -0.068
ENSMUSG00000026074 E048 125.0128162 0.0026420631 0.778424236 0.97903220 1 40049717 40049837 121 + 2.093 2.107 0.046
ENSMUSG00000026074 E049 210.7582431 0.0027066161 0.198753889 0.77466272 1 40050810 40051001 192 + 2.301 2.347 0.151
ENSMUSG00000026074 E050 17.4128793 0.0029105176 0.942669144 0.99989937 1 40053012 40053265 254 + 1.267 1.264 -0.013
ENSMUSG00000026074 E051 112.7925603 0.0001966807 0.738940259 0.97290014 1 40053266 40053383 118 + 2.061 2.052 -0.029
ENSMUSG00000026074 E052 118.6974309 0.0002042914 0.893259647 0.99549749 1 40053687 40053857 171 + 2.075 2.081 0.022
ENSMUSG00000026074 E053 0.0000000       1 40053858 40053858 1 +      
ENSMUSG00000026074 E054 96.1069950 0.0002554967 0.517746576 0.93149289 1 40056270 40056413 144 + 1.973 1.999 0.086
ENSMUSG00000026074 E055 117.4879996 0.0002164246 0.373064450 0.87811539 1 40058704 40058838 135 + 2.057 2.088 0.105
ENSMUSG00000026074 E056 0.4977100 0.5739320898 0.285768568   1 40058839 40058843 5 + 0.000 0.290 12.048
ENSMUSG00000026074 E057 85.4042961 0.0033871392 0.316227872 0.85266115 1 40060244 40060344 101 + 1.959 1.914 -0.149
ENSMUSG00000026074 E058 152.4533074 0.0035768776 0.343616246 0.87136849 1 40061865 40062014 150 + 2.203 2.168 -0.116
ENSMUSG00000026074 E059 3.2945770 0.0052805996 0.808879044 0.98304176 1 40062370 40062519 150 + 0.612 0.650 0.168
ENSMUSG00000026074 E060 187.8068947 0.0010270462 0.733314069 0.97232952 1 40062520 40062679 160 + 2.279 2.272 -0.023
ENSMUSG00000026074 E061 104.7544922 0.0007855798 0.805525250 0.98210805 1 40063470 40063609 140 + 2.018 2.029 0.037
ENSMUSG00000026074 E062 593.6811686 0.0024268252 0.325794803 0.86009064 1 40063789 40065470 1682 + 2.760 2.786 0.088

Help

Please Click HERE to learn more details about the results from DEXseq.