ENSMUSG00000028465

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENSMUST00000030187 ENSMUSG00000028465 Control shVgll3 Tln1 protein_coding protein_coding 38.75909 44.50949 33.00869 4.47595 1.794854 -0.4311544 11.155158 14.005941 8.304375 0.1987833 0.5487792 -0.7533888 0.28606667 0.32040000 0.25173333 -0.068666667 6.909512e-01 2.097209e-07 FALSE TRUE
ENSMUST00000126078 ENSMUSG00000028465 Control shVgll3 Tln1 protein_coding protein_coding_CDS_not_defined 38.75909 44.50949 33.00869 4.47595 1.794854 -0.4311544 1.529183 3.058367 0.000000 3.0583665 0.0000000 -8.2613270 0.02878333 0.05756667 0.00000000 -0.057566667 9.762485e-01 2.097209e-07   FALSE
ENSMUST00000127262 ENSMUSG00000028465 Control shVgll3 Tln1 protein_coding protein_coding_CDS_not_defined 38.75909 44.50949 33.00869 4.47595 1.794854 -0.4311544 2.177148 2.368483 1.985814 1.5888076 1.3408878 -0.2530647 0.05561667 0.05320000 0.05803333 0.004833333 1.000000e+00 2.097209e-07   FALSE
MSTRG.15859.2 ENSMUSG00000028465 Control shVgll3 Tln1 protein_coding   38.75909 44.50949 33.00869 4.47595 1.794854 -0.4311544 6.094843 5.097462 7.092223 0.4519831 0.1706586 0.4756642 0.16528333 0.11496667 0.21560000 0.100633333 2.097209e-07 2.097209e-07 FALSE TRUE
MSTRG.15859.3 ENSMUSG00000028465 Control shVgll3 Tln1 protein_coding   38.75909 44.50949 33.00869 4.47595 1.794854 -0.4311544 15.778580 17.349189 14.207971 0.2546545 0.5117997 -0.2879840 0.41455000 0.39773333 0.43136667 0.033633333 9.706657e-01 2.097209e-07 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand shVgll3 Control log2fold_Control_shVgll3
ENSMUSG00000028465 E001 1.9754802 0.0255762020 0.840134951 0.98677151 4 43531519 43531528 10 - 0.452 0.487 0.179
ENSMUSG00000028465 E002 1100.8069772 0.0021272855 0.789978548 0.98020403 4 43531529 43532085 557 - 3.043 3.037 -0.018
ENSMUSG00000028465 E003 202.4862789 0.0039720335 0.624735849 0.95514198 4 43532192 43532320 129 - 2.297 2.314 0.059
ENSMUSG00000028465 E004 201.1173207 0.0001285724 0.791274905 0.98058592 4 43532830 43533012 183 - 2.307 2.300 -0.023
ENSMUSG00000028465 E005 92.4452276 0.0002183517 0.769140234 0.97799068 4 43533126 43533188 63 - 1.962 1.973 0.036
ENSMUSG00000028465 E006 118.2388027 0.0001839592 0.668688706 0.95961628 4 43533304 43533429 126 - 2.067 2.080 0.046
ENSMUSG00000028465 E007 122.0456275 0.0005221359 0.678572365 0.96180777 4 43533554 43533678 125 - 2.096 2.081 -0.047
ENSMUSG00000028465 E008 166.3978285 0.0001570999 0.415540451 0.89937605 4 43533863 43533968 106 - 2.234 2.211 -0.076
ENSMUSG00000028465 E009 210.4705279 0.0002405372 0.954669421 1.00000000 4 43534390 43534497 108 - 2.324 2.322 -0.006
ENSMUSG00000028465 E010 243.5119856 0.0001281826 0.613326042 0.95421876 4 43534580 43534765 186 - 2.380 2.391 0.038
ENSMUSG00000028465 E011 157.4817599 0.0003419021 0.465760358 0.91864397 4 43535520 43535636 117 - 2.186 2.207 0.071
ENSMUSG00000028465 E012 161.7155357 0.0043131663 0.880478919 0.99189545 4 43535738 43535863 126 - 2.206 2.211 0.019
ENSMUSG00000028465 E013 222.4008141 0.0001376955 0.487014990 0.92579672 4 43535953 43536136 184 - 2.356 2.339 -0.056
ENSMUSG00000028465 E014 193.6887293 0.0007843555 0.105395425 0.64292956 4 43536244 43536410 167 - 2.312 2.266 -0.155
ENSMUSG00000028465 E015 152.9788552 0.0003566541 0.211920968 0.78415341 4 43536524 43536670 147 - 2.205 2.168 -0.124
ENSMUSG00000028465 E016 160.1199955 0.0001595082 0.293382749 0.83803329 4 43537788 43537907 120 - 2.221 2.191 -0.100
ENSMUSG00000028465 E017 119.7131147 0.0002455721 0.111554159 0.65453028 4 43537986 43538087 102 - 2.050 2.102 0.175
ENSMUSG00000028465 E018 150.9591849 0.0015723324 0.983015470 1.00000000 4 43538190 43538339 150 - 2.179 2.179 0.002
ENSMUSG00000028465 E019 156.1142826 0.0006976945 0.181346401 0.76062754 4 43538432 43538602 171 - 2.216 2.175 -0.137
ENSMUSG00000028465 E020 116.4797399 0.0006649442 0.195873582 0.77082536 4 43538678 43538779 102 - 2.092 2.047 -0.150
ENSMUSG00000028465 E021 117.8474010 0.0002597948 0.256661833 0.81059129 4 43539091 43539223 133 - 2.051 2.089 0.126
ENSMUSG00000028465 E022 195.2776689 0.0012753217 0.108660207 0.64918646 4 43539366 43539547 182 - 2.317 2.268 -0.161
ENSMUSG00000028465 E023 168.3054311 0.0003892498 0.518719751 0.93149289 4 43539637 43539777 141 - 2.216 2.234 0.061
ENSMUSG00000028465 E024 150.2806934 0.0001660201 0.148304253 0.71571101 4 43539976 43540137 162 - 2.154 2.196 0.141
ENSMUSG00000028465 E025 102.3732496 0.0002516714 0.895980636 0.99560027 4 43540530 43540673 144 - 2.015 2.010 -0.016
ENSMUSG00000028465 E026 103.8187782 0.0018489548 0.153273493 0.72153928 4 43542481 43542603 123 - 2.049 1.992 -0.191
ENSMUSG00000028465 E027 101.1577724 0.0005549835 0.066633353 0.55637185 4 43542702 43542791 90 - 2.043 1.976 -0.225
ENSMUSG00000028465 E028 107.4755034 0.0057460384 0.388264288 0.88612996 4 43542875 43542968 94 - 2.011 2.050 0.132
ENSMUSG00000028465 E029 173.9383532 0.0005550322 0.538211474 0.93662476 4 43543144 43543283 140 - 2.231 2.248 0.058
ENSMUSG00000028465 E030 183.7345560 0.0029043094 0.920948078 0.99794653 4 43543436 43543633 198 - 2.266 2.262 -0.015
ENSMUSG00000028465 E031 128.2286357 0.0016587563 0.793721530 0.98063190 4 43543817 43543936 120 - 2.104 2.113 0.030
ENSMUSG00000028465 E032 174.5067707 0.0032106581 0.595388800 0.95165770 4 43544280 43544488 209 - 2.254 2.232 -0.075
ENSMUSG00000028465 E033 87.9929405 0.0075606386 0.764223180 0.97799068 4 43544576 43544678 103 - 1.957 1.940 -0.056
ENSMUSG00000028465 E034 120.6579452 0.0002023772 0.324322192 0.85863487 4 43544841 43544969 129 - 2.101 2.068 -0.108
ENSMUSG00000028465 E035 99.6396417 0.0002209019 0.480022152 0.92327994 4 43545094 43545228 135 - 2.014 1.989 -0.085
ENSMUSG00000028465 E036 21.6520188 0.0164174156 0.451645834 0.91349987 4 43545407 43545409 3 - 1.393 1.319 -0.260
ENSMUSG00000028465 E037 80.6940327 0.0007704817 0.117812625 0.66364867 4 43545410 43545520 111 - 1.945 1.880 -0.216
ENSMUSG00000028465 E038 36.9971473 0.0004902047 0.405723669 0.89347807 4 43545606 43545647 42 - 1.603 1.556 -0.163
ENSMUSG00000028465 E039 57.0366550 0.0003464535 0.081806032 0.60137671 4 43545648 43545715 68 - 1.715 1.796 0.277
ENSMUSG00000028465 E040 29.7768966 0.0006587516 0.002900214 0.09978441 4 43545716 43545722 7 - 1.367 1.563 0.672
ENSMUSG00000028465 E041 80.5183309 0.0003445219 0.003832186 0.11989769 4 43545860 43545988 129 - 1.841 1.958 0.392
ENSMUSG00000028465 E042 50.4244262 0.0014853721 0.097809304 0.63317139 4 43546750 43546821 72 - 1.659 1.746 0.296
ENSMUSG00000028465 E043 28.7746691 0.0097967390 0.304884178 0.84606428 4 43546822 43546851 30 - 1.425 1.506 0.279
ENSMUSG00000028465 E044 40.4678699 0.0068797247 0.284557387 0.83154939 4 43546852 43546916 65 - 1.575 1.646 0.242
ENSMUSG00000028465 E045 104.5620046 0.0002853520 0.192865632 0.76896461 4 43547502 43547601 100 - 1.996 2.041 0.153
ENSMUSG00000028465 E046 143.1417567 0.0001742875 0.858442048 0.98884244 4 43547602 43547796 195 - 2.159 2.154 -0.018
ENSMUSG00000028465 E047 86.1291941 0.0044304904 0.233999267 0.80378281 4 43547979 43548122 144 - 1.905 1.963 0.197
ENSMUSG00000028465 E048 35.4839389 0.0011719600 0.628900603 0.95595792 4 43548123 43548146 24 - 1.544 1.573 0.099
ENSMUSG00000028465 E049 3.1219621 0.0062761008 0.500979630 0.92783507 4 43548147 43548197 51 - 0.668 0.564 -0.456
ENSMUSG00000028465 E050 91.5695249 0.0002319059 0.117025327 0.66203098 4 43549086 43549184 99 - 1.996 1.937 -0.196
ENSMUSG00000028465 E051 115.3376454 0.0002119889 0.536843204 0.93662476 4 43549321 43549529 209 - 2.075 2.054 -0.069
ENSMUSG00000028465 E052 63.3114851 0.0009640557 0.259252776 0.81353043 4 43549723 43549831 109 - 1.834 1.782 -0.177
ENSMUSG00000028465 E053 81.6467341 0.0078125752 0.988496058 1.00000000 4 43549938 43550051 114 - 1.914 1.916 0.005
ENSMUSG00000028465 E054 175.6408842 0.0001490791 0.671954934 0.96111497 4 43550198 43550378 181 - 2.239 2.250 0.037
ENSMUSG00000028465 E055 90.6466724 0.0002716777 0.117206664 0.66203938 4 43550962 43551038 77 - 1.926 1.985 0.198
ENSMUSG00000028465 E056 56.3988806 0.0004036701 0.181904528 0.76082247 4 43551186 43551287 102 - 1.721 1.784 0.214
ENSMUSG00000028465 E057 95.9617598 0.0004492053 0.817377907 0.98411089 4 43552986 43553141 156 - 1.979 1.988 0.028
ENSMUSG00000028465 E058 24.3646900 0.0009733969 0.968198356 1.00000000 4 43553446 43553450 5 - 1.400 1.403 0.009
ENSMUSG00000028465 E059 73.1035629 0.0012827148 0.645703997 0.95668705 4 43553451 43553550 100 - 1.879 1.858 -0.070
ENSMUSG00000028465 E060 36.0307863 0.0079554980 0.920983815 0.99794653 4 43554278 43554338 61 - 1.570 1.563 -0.026
ENSMUSG00000028465 E061 1.7981764 0.2531979490 0.998969353 1.00000000 4 43554339 43554451 113 - 0.450 0.443 -0.036
ENSMUSG00000028465 E062 6.4064652 0.0092385426 0.634928869 0.95663250 4 43554514 43555046 533 - 0.900 0.840 -0.231
ENSMUSG00000028465 E063 55.2489637 0.0005672709 0.802826392 0.98165184 4 43555047 43555105 59 - 1.741 1.753 0.041
ENSMUSG00000028465 E064 62.1412085 0.0029089764 0.376459427 0.87961444 4 43555106 43555174 69 - 1.772 1.818 0.157
ENSMUSG00000028465 E065 98.7525695 0.0034914502 0.728559513 0.97107356 4 43555269 43555411 143 - 1.988 2.004 0.057
ENSMUSG00000028465 E066 0.0000000       4 43555564 43555601 38 -      
ENSMUSG00000028465 E067 131.7710236 0.0077320832 0.706877615 0.96603614 4 43555602 43555754 153 - 2.109 2.130 0.070
ENSMUSG00000028465 E068 98.5182232 0.0006224398 0.433360338 0.90866138 4 43555855 43555984 130 - 1.979 2.008 0.098
ENSMUSG00000028465 E069 72.2654389 0.0057275637 0.812500187 0.98376893 4 43556289 43556386 98 - 1.870 1.856 -0.047
ENSMUSG00000028465 E070 78.9435387 0.0002707661 0.171313977 0.75034489 4 43556621 43556783 163 - 1.930 1.875 -0.184
ENSMUSG00000028465 E071 0.9894272 0.2705705195 0.386351218 0.88546179 4 43558381 43558460 80 - 0.392 0.202 -1.313
ENSMUSG00000028465 E072 14.1616432 0.0230626124 0.002049710 0.08046142 4 43559343 43559717 375 - 0.939 1.306 1.324
ENSMUSG00000028465 E073 39.3064199 0.0219366970 0.589215766 0.95124454 4 43562130 43562691 562 - 1.579 1.622 0.144

Help

Please Click HERE to learn more details about the results from DEXseq.