ENSMUSG00000032393

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENSMUST00000034960 ENSMUSG00000032393 Control shVgll3 Dpp8 protein_coding protein_coding 13.84037 14.711 12.96973 0.5435369 0.6589217 -0.1816156 5.5043222 5.7001171 5.3085272 1.02235895 0.18887612 -0.1024936 0.40336667 0.39390000 0.41283333 0.01893333 1.0000000000 0.0006127848 FALSE TRUE
ENSMUST00000214247 ENSMUSG00000032393 Control shVgll3 Dpp8 protein_coding retained_intron 13.84037 14.711 12.96973 0.5435369 0.6589217 -0.1816156 0.9812851 0.3811214 1.5814488 0.38112135 0.77204274 2.0246525 0.07183333 0.02496667 0.11870000 0.09373333 0.6174404521 0.0006127848 FALSE TRUE
ENSMUST00000217328 ENSMUSG00000032393 Control shVgll3 Dpp8 protein_coding protein_coding_CDS_not_defined 13.84037 14.711 12.96973 0.5435369 0.6589217 -0.1816156 1.2159329 1.6260700 0.8057959 0.81450791 0.59053993 -1.0039544 0.08455000 0.10660000 0.06250000 -0.04410000 0.9830675577 0.0006127848 FALSE TRUE
MSTRG.23809.1 ENSMUSG00000032393 Control shVgll3 Dpp8 protein_coding   13.84037 14.711 12.96973 0.5435369 0.6589217 -0.1816156 0.9669397 0.9159355 1.0179439 0.05221898 0.13249705 0.1507779 0.07080000 0.06226667 0.07933333 0.01706667 0.9706656688 0.0006127848 TRUE TRUE
MSTRG.23809.2 ENSMUSG00000032393 Control shVgll3 Dpp8 protein_coding   13.84037 14.711 12.96973 0.5435369 0.6589217 -0.1816156 0.8126142 0.3739245 1.2513040 0.37392451 0.27549072 1.7160214 0.05985000 0.02453333 0.09516667 0.07063333 0.6160854520 0.0006127848 FALSE TRUE
MSTRG.23809.4 ENSMUSG00000032393 Control shVgll3 Dpp8 protein_coding   13.84037 14.711 12.96973 0.5435369 0.6589217 -0.1816156 1.5235455 1.7070610 1.3400300 0.23882251 0.26792387 -0.3469499 0.11020000 0.11756667 0.10283333 -0.01473333 0.9829651812 0.0006127848 TRUE TRUE
MSTRG.23809.6 ENSMUSG00000032393 Control shVgll3 Dpp8 protein_coding   13.84037 14.711 12.96973 0.5435369 0.6589217 -0.1816156 2.4637105 3.5204546 1.4069663 0.38064718 0.07093029 -1.3170485 0.17350000 0.23803333 0.10896667 -0.12906667 0.0006127848 0.0006127848 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand shVgll3 Control log2fold_Control_shVgll3
ENSMUSG00000032393 E001 0.1613534 0.0344942629 4.019284e-01   9 64939678 64939695 18 + 0.136 0.000 -9.662
ENSMUSG00000032393 E002 0.3227068 0.3257294124 2.196336e-01   9 64939696 64939712 17 + 0.238 0.000 -11.818
ENSMUSG00000032393 E003 1.3059116 0.0192986709 7.757256e-01 9.785258e-01 9 64939713 64939725 13 + 0.392 0.339 -0.309
ENSMUSG00000032393 E004 39.8459160 0.0004685644 1.130319e-01 6.567823e-01 9 64939726 64939905 180 + 1.656 1.566 -0.309
ENSMUSG00000032393 E005 9.0339410 0.0020467184 9.319282e-01 9.993033e-01 9 64939906 64940003 98 + 1.007 0.994 -0.046
ENSMUSG00000032393 E006 3.6107453 0.0119459255 3.829130e-01 8.834420e-01 9 64940004 64940059 56 + 0.732 0.597 -0.572
ENSMUSG00000032393 E007 3.4490361 0.0948713316 2.287448e-01 8.009148e-01 9 64940060 64940104 45 + 0.760 0.527 -1.007
ENSMUSG00000032393 E008 9.2158784 0.0270959159 6.515435e-01 9.566871e-01 9 64940105 64940208 104 + 1.037 0.981 -0.205
ENSMUSG00000032393 E009 140.2327557 0.0002172445 1.932321e-01 7.691151e-01 9 64940209 64942156 1948 + 2.128 2.163 0.117
ENSMUSG00000032393 E010 37.3723070 0.0005898900 1.720381e-02 2.968291e-01 9 64942157 64942293 137 + 1.653 1.514 -0.475
ENSMUSG00000032393 E011 76.2218086 0.0216578884 3.968377e-01 8.891290e-01 9 64944251 64944523 273 + 1.924 1.850 -0.248
ENSMUSG00000032393 E012 57.5058473 0.0169737524 1.912656e-01 7.668320e-01 9 64949546 64949658 113 + 1.822 1.712 -0.370
ENSMUSG00000032393 E013 77.8876810 0.0110318596 9.176035e-01 9.976865e-01 9 64950968 64951141 174 + 1.894 1.895 0.002
ENSMUSG00000032393 E014 11.0529137 0.0098368429 8.306320e-01 9.854840e-01 9 64952902 64952907 6 + 1.092 1.066 -0.093
ENSMUSG00000032393 E015 60.8981576 0.0003130535 6.234108e-02 5.442283e-01 9 64952908 64953070 163 + 1.835 1.748 -0.293
ENSMUSG00000032393 E016 35.8118728 0.0030593337 4.605276e-02 4.763264e-01 9 64958672 64958782 111 + 1.631 1.502 -0.441
ENSMUSG00000032393 E017 0.3318168 0.0287469969 8.805834e-01   9 64959873 64960326 454 + 0.136 0.112 -0.309
ENSMUSG00000032393 E018 48.1806122 0.0064492908 4.166841e-01 9.005062e-01 9 64960327 64960455 129 + 1.663 1.710 0.159
ENSMUSG00000032393 E019 0.4891790 0.2240403489 7.476419e-01   9 64960456 64961050 595 + 0.136 0.201 0.687
ENSMUSG00000032393 E020 25.3151902 0.0010261490 2.118281e-01 7.841534e-01 9 64961051 64961112 62 + 1.465 1.376 -0.309
ENSMUSG00000032393 E021 0.4933433 0.0219537952 4.540153e-01   9 64961113 64961700 588 + 0.239 0.112 -1.309
ENSMUSG00000032393 E022 37.5563393 0.0129189759 6.829567e-01 9.629190e-01 9 64961701 64961801 101 + 1.604 1.566 -0.132
ENSMUSG00000032393 E023 0.8275049 0.0878781606 1.368035e-01 6.993652e-01 9 64961802 64962109 308 + 0.392 0.113 -2.309
ENSMUSG00000032393 E024 20.5740353 0.0613253945 5.302088e-01 9.357450e-01 9 64962110 64962287 178 + 1.294 1.360 0.228
ENSMUSG00000032393 E025 0.4941990 0.0219218418 6.917352e-01   9 64962288 64963073 786 + 0.136 0.202 0.691
ENSMUSG00000032393 E026 69.5827999 0.0013074440 8.601102e-01 9.888424e-01 9 64963074 64963233 160 + 1.844 1.848 0.013
ENSMUSG00000032393 E027 0.1613534 0.0344942629 4.019284e-01   9 64963234 64963736 503 + 0.136 0.000 -11.712
ENSMUSG00000032393 E028 0.0000000       9 64967057 64967228 172 +      
ENSMUSG00000032393 E029 41.5932872 0.0120259674 5.649195e-01 9.421718e-01 9 64967485 64967564 80 + 1.653 1.605 -0.160
ENSMUSG00000032393 E030 78.3314695 0.0043797219 3.556006e-01 8.751770e-01 9 64970709 64970861 153 + 1.923 1.875 -0.163
ENSMUSG00000032393 E031 66.6765881 0.0076297618 3.573543e-01 8.751770e-01 9 64971101 64971236 136 + 1.860 1.802 -0.195
ENSMUSG00000032393 E032 1.8185881 0.0092288120 5.273856e-01 9.357450e-01 9 64972095 64973632 1538 + 0.505 0.394 -0.572
ENSMUSG00000032393 E033 0.1613534 0.0344942629 4.019284e-01   9 64973633 64973778 146 + 0.136 0.000 -11.712
ENSMUSG00000032393 E034 2.9656084 0.0328872809 6.485739e-01 9.566871e-01 9 64973779 64975187 1409 + 0.552 0.629 0.344
ENSMUSG00000032393 E035 52.3449801 0.0004581988 3.545171e-01 8.751770e-01 9 64981721 64981867 147 + 1.751 1.702 -0.164
ENSMUSG00000032393 E036 5.5976109 0.0032666928 8.020089e-01 9.816518e-01 9 64982225 64982284 60 + 0.836 0.801 -0.139
ENSMUSG00000032393 E037 7.5555181 0.0024921272 9.166886e-01 9.976865e-01 9 64982285 64982410 126 + 0.939 0.924 -0.057
ENSMUSG00000032393 E038 24.1551080 0.0012562768 1.954458e-01 7.708254e-01 9 64982411 64982750 340 + 1.449 1.354 -0.329
ENSMUSG00000032393 E039 20.9021768 0.0031225209 4.158074e-04 2.494418e-02 9 64982751 64983017 267 + 1.471 1.190 -0.979
ENSMUSG00000032393 E040 18.7628179 0.0031356188 2.951214e-01 8.383291e-01 9 64983018 64983029 12 + 1.340 1.252 -0.309
ENSMUSG00000032393 E041 69.4866543 0.0003055918 4.722897e-01 9.211144e-01 9 64983030 64983170 141 + 1.830 1.857 0.090
ENSMUSG00000032393 E042 102.5213334 0.0002119755 8.351247e-01 9.860997e-01 9 64985245 64985387 143 + 2.011 2.014 0.012
ENSMUSG00000032393 E043 80.6516172 0.0002951503 3.161411e-01 8.526612e-01 9 64985956 64986067 112 + 1.933 1.890 -0.144
ENSMUSG00000032393 E044 584.7281329 0.0003584069 6.078237e-01 9.533477e-01 9 64988013 64989739 1727 + 2.763 2.767 0.012
ENSMUSG00000032393 E045 91.5671928 0.0002461595 3.819405e-05 3.603178e-03 9 64989740 64990154 415 + 1.875 2.025 0.504
ENSMUSG00000032393 E046 234.2017175 0.0003656539 6.333378e-09 1.610606e-06 9 64990155 64991785 1631 + 2.289 2.424 0.450

Help

Please Click HERE to learn more details about the results from DEXseq.