ENSMUSG00000033257

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENSMUST00000042125 ENSMUSG00000033257 Control shVgll3 Ttll4 protein_coding protein_coding 6.425347 5.582933 7.267762 0.2946144 0.320841 0.3798898 2.1435590 1.849627 2.4374913 0.03055991 0.41982491 0.3962908 0.3339333 0.3328000 0.3350667 0.002266667 1.000000000 0.000167631 FALSE  
ENSMUST00000128891 ENSMUSG00000033257 Control shVgll3 Ttll4 protein_coding retained_intron 6.425347 5.582933 7.267762 0.2946144 0.320841 0.3798898 0.4218242 0.499955 0.3436935 0.05205794 0.05985179 -0.5278704 0.0688500 0.0908000 0.0469000 -0.043900000 0.691338433 0.000167631 FALSE  
ENSMUST00000153636 ENSMUSG00000033257 Control shVgll3 Ttll4 protein_coding retained_intron 6.425347 5.582933 7.267762 0.2946144 0.320841 0.3798898 0.2390987 0.000000 0.4781973 0.00000000 0.06282241 5.6093925 0.0327500 0.0000000 0.0655000 0.065500000 0.000167631 0.000167631    
ENSMUST00000155753 ENSMUSG00000033257 Control shVgll3 Ttll4 protein_coding retained_intron 6.425347 5.582933 7.267762 0.2946144 0.320841 0.3798898 1.2955425 1.185915 1.4051701 0.15865784 0.07010433 0.2428607 0.2020833 0.2105000 0.1936667 -0.016833333 0.973369962 0.000167631 FALSE  
MSTRG.610.3 ENSMUSG00000033257 Control shVgll3 Ttll4 protein_coding   6.425347 5.582933 7.267762 0.2946144 0.320841 0.3798898 2.0199346 1.691735 2.3481340 0.10043577 0.27680943 0.4706392 0.3139000 0.3034667 0.3243333 0.020866667 0.995581157 0.000167631 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand shVgll3 Control log2fold_Control_shVgll3
ENSMUSG00000033257 E001 0.3318067 0.3183988700 0.201422458   1 74700904 74700908 5 + 0.000 0.248 10.326
ENSMUSG00000033257 E002 0.8303729 0.0172663504 0.458125922 0.91646450 1 74700909 74700939 31 + 0.194 0.333 1.029
ENSMUSG00000033257 E003 4.6205847 0.0090188467 0.122208209 0.67085264 1 74700940 74700975 36 + 0.822 0.610 -0.878
ENSMUSG00000033257 E004 8.6923921 0.0276828099 0.647884418 0.95668705 1 74700976 74701048 73 + 1.001 0.957 -0.164
ENSMUSG00000033257 E005 15.9354429 0.0012307053 0.692438527 0.96350016 1 74712003 74712169 167 + 1.233 1.214 -0.067
ENSMUSG00000033257 E006 1.4879640 0.0108162091 0.002880523 0.09939928 1 74712170 74712414 245 + 0.549 0.000 -15.611
ENSMUSG00000033257 E007 5.2617084 0.0413343313 0.528048350 0.93574499 1 74718057 74718090 34 + 0.741 0.854 0.445
ENSMUSG00000033257 E008 199.7658434 0.0001649203 0.001580011 0.06922459 1 74718091 74719512 1422 + 2.322 2.261 -0.204
ENSMUSG00000033257 E009 14.1565436 0.0013197331 0.547123805 0.93707028 1 74719513 74719622 110 + 1.145 1.214 0.242
ENSMUSG00000033257 E010 49.9683754 0.0005038619 0.390137351 0.88635206 1 74719623 74720458 836 + 1.714 1.687 -0.094
ENSMUSG00000033257 E011 20.9148224 0.0008884759 0.988274031 1.00000000 1 74720459 74720568 110 + 1.329 1.345 0.055
ENSMUSG00000033257 E012 15.2906517 0.0013838924 0.647448834 0.95668705 1 74720918 74720981 64 + 1.218 1.193 -0.089
ENSMUSG00000033257 E013 8.4022035 0.0022165675 0.768771453 0.97799068 1 74724478 74724484 7 + 0.976 0.957 -0.071
ENSMUSG00000033257 E014 19.9367313 0.0116607321 0.508628152 0.93082987 1 74724485 74724602 118 + 1.334 1.288 -0.161
ENSMUSG00000033257 E015 10.8386273 0.0020475601 0.894518293 0.99560027 1 74725019 74725114 96 + 1.069 1.070 0.004
ENSMUSG00000033257 E016 4.7744045 0.0421905813 0.606863495 0.95334770 1 74725115 74725129 15 + 0.784 0.718 -0.264
ENSMUSG00000033257 E017 11.8649357 0.0016143787 0.329536141 0.86241242 1 74725476 74725552 77 + 1.137 1.055 -0.293
ENSMUSG00000033257 E018 24.3771479 0.0007929377 0.621386520 0.95514198 1 74726363 74726554 192 + 1.378 1.427 0.170
ENSMUSG00000033257 E019 15.3162461 0.0012467603 0.869955911 0.98928203 1 74726637 74726719 83 + 1.195 1.224 0.101
ENSMUSG00000033257 E020 21.2516432 0.0009884929 0.697448407 0.96475389 1 74726882 74727010 129 + 1.323 1.367 0.152
ENSMUSG00000033257 E021 21.7174339 0.0008723345 0.230541363 0.80378281 1 74727323 74727445 123 + 1.305 1.408 0.356
ENSMUSG00000033257 E022 21.0791440 0.0010358236 0.554922177 0.93902497 1 74727726 74727824 99 + 1.351 1.321 -0.103
ENSMUSG00000033257 E023 32.0754473 0.0012918400 0.238187441 0.80442163 1 74728482 74728581 100 + 1.539 1.480 -0.203
ENSMUSG00000033257 E024 18.2216063 0.0045301164 0.714346591 0.96841481 1 74728582 74728616 35 + 1.286 1.271 -0.055
ENSMUSG00000033257 E025 28.9652097 0.0008724199 0.538542041 0.93662476 1 74729119 74729231 113 + 1.482 1.457 -0.087
ENSMUSG00000033257 E026 12.8269687 0.0029754223 0.131617358 0.68818678 1 74729232 74729265 34 + 1.187 1.055 -0.474
ENSMUSG00000033257 E027 16.8030523 0.0011719384 0.861016040 0.98884244 1 74729266 74729837 572 + 1.233 1.262 0.103
ENSMUSG00000033257 E028 4.7815608 0.0040880178 0.102193109 0.63968618 1 74729853 74730048 196 + 0.642 0.876 0.946
ENSMUSG00000033257 E029 9.7158095 0.0020005701 0.094921452 0.63028921 1 74734372 74734866 495 + 0.935 1.123 0.689
ENSMUSG00000033257 E030 16.1127559 0.0012090273 0.630904701 0.95623770 1 74734867 74734892 26 + 1.240 1.214 -0.092
ENSMUSG00000033257 E031 26.9493858 0.0024967868 0.768365775 0.97799068 1 74734893 74734969 77 + 1.444 1.439 -0.018
ENSMUSG00000033257 E032 30.6439383 0.0006928922 0.721181995 0.97058899 1 74735564 74735774 211 + 1.498 1.490 -0.026
ENSMUSG00000033257 E033 19.0847516 0.0012224879 0.251668483 0.80641511 1 74735901 74735971 71 + 1.329 1.253 -0.267
ENSMUSG00000033257 E034 26.1934502 0.0071021260 0.053980382 0.50914940 1 74736338 74736408 71 + 1.482 1.344 -0.476
ENSMUSG00000033257 E035 761.8622370 0.0019593627 0.004266299 0.12862671 1 74736600 74742889 6290 + 2.853 2.908 0.183

Help

Please Click HERE to learn more details about the results from DEXseq.