ENSMUSG00000035949

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENSMUST00000091020 ENSMUSG00000035949 Control shVgll3 Fbxw2 protein_coding protein_coding 25.33144 26.12324 24.53964 1.028822 0.4164359 -0.090184 1.384523 0.000000 2.7690468 0.0000000 0.57369457 8.1184463 0.05685 0.00000000 0.11370000 0.113700000 3.041452e-12 3.041452e-12 FALSE TRUE
ENSMUST00000113075 ENSMUSG00000035949 Control shVgll3 Fbxw2 protein_coding protein_coding 25.33144 26.12324 24.53964 1.028822 0.4164359 -0.090184 1.360271 1.472472 1.2480694 0.1467997 0.03850803 -0.2367936 0.05370 0.05646667 0.05093333 -0.005533333 9.710093e-01 3.041452e-12 FALSE TRUE
ENSMUST00000113080 ENSMUSG00000035949 Control shVgll3 Fbxw2 protein_coding protein_coding 25.33144 26.12324 24.53964 1.028822 0.4164359 -0.090184 8.665305 10.148783 7.1818263 0.4878952 0.49516279 -0.4982975 0.34225 0.39100000 0.29350000 -0.097500000 6.200569e-01 3.041452e-12 FALSE TRUE
ENSMUST00000131534 ENSMUSG00000035949 Control shVgll3 Fbxw2 protein_coding protein_coding_CDS_not_defined 25.33144 26.12324 24.53964 1.028822 0.4164359 -0.090184 7.457940 6.899444 8.0164363 0.2476741 0.19673978 0.2161900 0.29575 0.26483333 0.32666667 0.061833333 4.997065e-01 3.041452e-12 FALSE TRUE
ENSMUST00000145180 ENSMUSG00000035949 Control shVgll3 Fbxw2 protein_coding protein_coding_CDS_not_defined 25.33144 26.12324 24.53964 1.028822 0.4164359 -0.090184 1.780639 2.746659 0.8146202 1.0923461 0.81462024 -1.7411189 0.06715 0.10213333 0.03216667 -0.069966667 6.375377e-01 3.041452e-12   FALSE
ENSMUST00000156130 ENSMUSG00000035949 Control shVgll3 Fbxw2 protein_coding protein_coding_CDS_not_defined 25.33144 26.12324 24.53964 1.028822 0.4164359 -0.090184 1.582809 1.697045 1.4685735 0.1810553 0.06406501 -0.2072951 0.06240 0.06490000 0.05990000 -0.005000000 9.794411e-01 3.041452e-12 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand shVgll3 Control log2fold_Control_shVgll3
ENSMUSG00000035949 E001 26.326747 0.0007245878 0.131814170 0.68828280 2 34694526 34695189 664 - 1.385 1.483 0.341
ENSMUSG00000035949 E002 9.041410 0.0030328059 0.385736927 0.88539078 2 34695190 34695349 160 - 1.047 0.951 -0.354
ENSMUSG00000035949 E003 2.791827 0.0061539292 0.491737355 0.92674629 2 34695350 34695350 1 - 0.631 0.521 -0.499
ENSMUSG00000035949 E004 2.791827 0.0061539292 0.491737355 0.92674629 2 34695351 34695352 2 - 0.631 0.521 -0.499
ENSMUSG00000035949 E005 227.831489 0.0001461698 0.064855318 0.55136447 2 34695353 34696011 659 - 2.340 2.378 0.128
ENSMUSG00000035949 E006 36.226612 0.0005774404 0.187510637 0.76561935 2 34696265 34697289 1025 - 1.532 1.606 0.252
ENSMUSG00000035949 E007 82.596266 0.0012947410 0.001913573 0.07639924 2 34697290 34697459 170 - 1.856 1.981 0.420
ENSMUSG00000035949 E008 49.385603 0.0004045250 0.241921748 0.80442163 2 34698526 34698612 87 - 1.674 1.729 0.189
ENSMUSG00000035949 E009 2.932338 0.3894595392 0.145163197 0.71005403 2 34698613 34698675 63 - 0.362 0.749 1.827
ENSMUSG00000035949 E010 71.406734 0.0003604711 0.478682445 0.92326912 2 34700995 34701128 134 - 1.875 1.844 -0.104
ENSMUSG00000035949 E011 180.150844 0.0001758283 0.018467360 0.30642719 2 34701851 34702749 899 - 2.287 2.226 -0.204
ENSMUSG00000035949 E012 15.945580 0.0013066986 0.978497244 1.00000000 2 34702750 34702826 77 - 1.231 1.227 -0.014
ENSMUSG00000035949 E013 151.472959 0.0049571310 0.254230081 0.80748514 2 34702827 34703021 195 - 2.206 2.159 -0.158
ENSMUSG00000035949 E014 7.912455 0.0137324735 0.961661157 1.00000000 2 34705280 34706135 856 - 0.947 0.951 0.016
ENSMUSG00000035949 E015 1.812183 0.0089103321 0.124168849 0.67465267 2 34711815 34712569 755 - 0.297 0.562 1.430
ENSMUSG00000035949 E016 63.242410 0.0017013218 0.096695770 0.63170379 2 34712570 34712615 46 - 1.846 1.765 -0.271
ENSMUSG00000035949 E017 261.959007 0.0002635060 0.856806380 0.98867271 2 34712616 34712987 372 - 2.422 2.417 -0.019
ENSMUSG00000035949 E018 57.632973 0.0003560755 0.775012616 0.97842624 2 34712988 34713079 92 - 1.775 1.760 -0.051
ENSMUSG00000035949 E019 37.984900 0.0005041470 0.385031931 0.88471882 2 34713080 34715274 2195 - 1.616 1.565 -0.172
ENSMUSG00000035949 E020 7.884731 0.1259458577 0.248937878 0.80516260 2 34715275 34715691 417 - 1.047 0.821 -0.851
ENSMUSG00000035949 E021 9.898431 0.0020468403 0.845441439 0.98686918 2 34715692 34715973 282 - 1.047 1.025 -0.081
ENSMUSG00000035949 E022 59.560352 0.0013641024 0.868083196 0.98892123 2 34715974 34716082 109 - 1.787 1.777 -0.033
ENSMUSG00000035949 E023 1.300506 0.3507061051 0.552489206 0.93803154 2 34716083 34716183 101 - 0.296 0.423 0.756
ENSMUSG00000035949 E024 18.284014 0.0010468496 0.193748034 0.76956650 2 34716184 34716323 140 - 1.231 1.333 0.355

Help

Please Click HERE to learn more details about the results from DEXseq.