ENSMUSG00000037108

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENSMUST00000035852 ENSMUSG00000037108 Control shVgll3 Zcwpw1 protein_coding protein_coding 8.724275 6.799756 10.64879 0.2138857 0.3073761 0.6463694 5.8311108 4.853386 6.808836 0.28520353 0.3864645 0.4875644 0.6774333 0.7125667 0.6423000 -0.07026667 9.706657e-01 7.626953e-06 FALSE TRUE
ENSMUST00000127541 ENSMUSG00000037108 Control shVgll3 Zcwpw1 protein_coding retained_intron 8.724275 6.799756 10.64879 0.2138857 0.3073761 0.6463694 2.1214737 1.836246 2.406701 0.08296456 0.3339818 0.3884445 0.2479000 0.2712333 0.2245667 -0.04666667 9.706657e-01 7.626953e-06   FALSE
ENSMUST00000141642 ENSMUSG00000037108 Control shVgll3 Zcwpw1 protein_coding protein_coding 8.724275 6.799756 10.64879 0.2138857 0.3073761 0.6463694 0.6614902 0.000000 1.322980 0.00000000 0.3973553 7.0585117 0.0614500 0.0000000 0.1229000 0.12290000 7.626953e-06 7.626953e-06 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand shVgll3 Control log2fold_Control_shVgll3
ENSMUSG00000037108 E001 20.407298 0.0009336883 0.002428855 0.08878985 5 137786060 137786207 148 + 1.405 1.164 -0.844
ENSMUSG00000037108 E002 0.000000       5 137790928 137793752 2825 +      
ENSMUSG00000037108 E003 14.009712 0.0014034249 0.335777128 0.86632573 5 137793753 137793807 55 + 1.201 1.114 -0.314
ENSMUSG00000037108 E004 0.000000       5 137793808 137794138 331 +      
ENSMUSG00000037108 E005 58.068604 0.0003667894 0.043232294 0.46308136 5 137794834 137795078 245 + 1.798 1.707 -0.306
ENSMUSG00000037108 E006 15.464066 0.0013369367 0.059364773 0.52850008 5 137796160 137796235 76 + 1.138 1.296 0.561
ENSMUSG00000037108 E007 12.023980 0.0016471778 0.556009780 0.93956091 5 137797451 137797679 229 + 1.129 1.072 -0.208
ENSMUSG00000037108 E008 8.069783 0.0026032699 0.356528962 0.87517695 5 137797680 137797769 90 + 0.906 1.008 0.384
ENSMUSG00000037108 E009 18.956234 0.0010730196 0.003308386 0.10977340 5 137797770 137797863 94 + 1.186 1.411 0.787
ENSMUSG00000037108 E010 28.344949 0.0007263313 0.302469913 0.84345484 5 137798248 137798405 158 + 1.432 1.497 0.224
ENSMUSG00000037108 E011 22.704741 0.0009193733 0.236603616 0.80442163 5 137799236 137799358 123 + 1.400 1.314 -0.300
ENSMUSG00000037108 E012 22.870415 0.0008728179 0.305164410 0.84612782 5 137808278 137808394 117 + 1.340 1.411 0.248
ENSMUSG00000037108 E013 12.164114 0.0017397399 0.095313867 0.63028921 5 137809075 137809090 16 + 1.042 1.198 0.561
ENSMUSG00000037108 E014 24.554423 0.0012479132 0.757200689 0.97648921 5 137809091 137809195 105 + 1.390 1.411 0.072
ENSMUSG00000037108 E015 18.970045 0.0039801503 0.790417688 0.98020843 5 137809837 137809912 76 + 1.282 1.305 0.080
ENSMUSG00000037108 E016 27.027149 0.0022521774 0.966645950 1.00000000 5 137810264 137810362 99 + 1.440 1.437 -0.010
ENSMUSG00000037108 E017 17.803843 0.0051004254 0.086591176 0.61353336 5 137815155 137815238 84 + 1.202 1.346 0.507
ENSMUSG00000037108 E018 12.364505 0.0164153816 0.779084152 0.97903220 5 137815720 137815786 67 + 1.129 1.100 -0.104
ENSMUSG00000037108 E019 25.640575 0.0008025032 0.616255833 0.95421876 5 137816060 137816154 95 + 1.405 1.437 0.113
ENSMUSG00000037108 E020 30.218606 0.0156301556 0.667966122 0.95947478 5 137817226 137817286 61 + 1.503 1.462 -0.141
ENSMUSG00000037108 E021 29.112097 0.0012252729 0.105184211 0.64252998 5 137817704 137817838 135 + 1.511 1.404 -0.366
ENSMUSG00000037108 E022 0.000000       5 137820416 137820883 468 +      

Help

Please Click HERE to learn more details about the results from DEXseq.