ENSMUSG00000043822

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENSMUST00000095446 ENSMUSG00000043822 Control shVgll3 Adamtsl5 protein_coding protein_coding 13.5785 10.22059 16.93642 0.7811251 0.8047523 0.7280911 2.177349 2.3007548 2.053943 0.4130061 0.48022314 -0.1629609 0.17260000 0.22570000 0.1195000 -0.10620000 0.5942655 0.0045039 FALSE TRUE
ENSMUST00000124789 ENSMUSG00000043822 Control shVgll3 Adamtsl5 protein_coding retained_intron 13.5785 10.22059 16.93642 0.7811251 0.8047523 0.7280911 2.949212 2.0581889 3.840235 0.4191801 0.31147164 0.8965786 0.21538333 0.20420000 0.2265667 0.02236667 0.9721909 0.0045039 TRUE TRUE
ENSMUST00000128845 ENSMUSG00000043822 Control shVgll3 Adamtsl5 protein_coding retained_intron 13.5785 10.22059 16.93642 0.7811251 0.8047523 0.7280911 1.632064 1.2386416 2.025486 0.3061982 0.02662256 0.7050138 0.12263333 0.12513333 0.1201333 -0.00500000 1.0000000 0.0045039   FALSE
MSTRG.2456.11 ENSMUSG00000043822 Control shVgll3 Adamtsl5 protein_coding   13.5785 10.22059 16.93642 0.7811251 0.8047523 0.7280911 3.367948 1.7951925 4.940704 0.1163208 0.19710312 1.4554809 0.23398333 0.17596667 0.2920000 0.11603333 0.0045039 0.0045039   FALSE
MSTRG.2456.12 ENSMUSG00000043822 Control shVgll3 Adamtsl5 protein_coding   13.5785 10.22059 16.93642 0.7811251 0.8047523 0.7280911 1.128950 0.7566633 1.501236 0.2492758 0.22322041 0.9790638 0.08081667 0.07223333 0.0894000 0.01716667 0.9706657 0.0045039   FALSE
MSTRG.2456.4 ENSMUSG00000043822 Control shVgll3 Adamtsl5 protein_coding   13.5785 10.22059 16.93642 0.7811251 0.8047523 0.7280911 1.393606 0.9728097 1.814402 0.1169131 0.24227582 0.8924398 0.10246667 0.09746667 0.1074667 0.01000000 0.9868408 0.0045039 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand shVgll3 Control log2fold_Control_shVgll3
ENSMUSG00000043822 E001 0.0000000       10 80174944 80174977 34 -      
ENSMUSG00000043822 E002 1.1441529 0.0440809397 0.2344064394 0.8037828 10 80175422 80175482 61 - 0.390 0.161 -1.702
ENSMUSG00000043822 E003 1.1475106 0.0831425111 0.6868256038 0.9629190 10 80175483 80175626 144 - 0.294 0.369 0.466
ENSMUSG00000043822 E004 0.8246307 0.2671519601 0.4117428882 0.8968301 10 80175627 80175654 28 - 0.172 0.369 1.467
ENSMUSG00000043822 E005 0.9859841 0.3068980282 0.6355894181 0.9566871 10 80175655 80175698 44 - 0.237 0.369 0.884
ENSMUSG00000043822 E006 0.8158866 0.0171637458 0.2662990674 0.8166443 10 80175699 80175699 1 - 0.172 0.369 1.463
ENSMUSG00000043822 E007 127.3242829 0.0001965665 0.5495094417 0.9370703 10 80175700 80176674 975 - 2.095 2.076 -0.064
ENSMUSG00000043822 E008 196.2369614 0.0002010589 0.1622554571 0.7351140 10 80176675 80177290 616 - 2.287 2.252 -0.119
ENSMUSG00000043822 E009 14.3178730 0.0041810203 0.6141239562 0.9542188 10 80177291 80177422 132 - 1.149 1.197 0.168
ENSMUSG00000043822 E010 60.5847930 0.0016338332 0.8756403025 0.9907353 10 80177423 80177494 72 - 1.773 1.764 -0.029
ENSMUSG00000043822 E011 106.8192510 0.0002382197 0.2022584573 0.7768696 10 80177577 80177775 199 - 1.997 2.041 0.147
ENSMUSG00000043822 E012 61.0772295 0.0014602797 0.8495440906 0.9871460 10 80177893 80178056 164 - 1.776 1.767 -0.030
ENSMUSG00000043822 E013 48.6917218 0.0004477282 0.8389637798 0.9867715 10 80178141 80178227 87 - 1.673 1.684 0.036
ENSMUSG00000043822 E014 55.2383598 0.0017793589 0.3602966036 0.8753500 10 80178228 80178324 97 - 1.747 1.700 -0.161
ENSMUSG00000043822 E015 119.3762930 0.0035967234 0.5279497440 0.9357450 10 80178325 80178533 209 - 2.071 2.043 -0.094
ENSMUSG00000043822 E016 34.1877091 0.0071066372 0.7231987895 0.9706264 10 80178534 80178572 39 - 1.538 1.508 -0.101
ENSMUSG00000043822 E017 59.7400991 0.0003602926 0.2725704238 0.8186210 10 80178573 80178742 170 - 1.782 1.729 -0.176
ENSMUSG00000043822 E018 39.8990514 0.0094205914 0.7309460089 0.9715998 10 80178743 80178839 97 - 1.584 1.609 0.087
ENSMUSG00000043822 E019 20.8481293 0.0080496247 0.4078370753 0.8946505 10 80178840 80178854 15 - 1.294 1.367 0.254
ENSMUSG00000043822 E020 54.3130788 0.0030418725 0.6450535772 0.9566871 10 80179433 80179560 128 - 1.714 1.740 0.089
ENSMUSG00000043822 E021 61.5320403 0.0003456517 0.0639434016 0.5490613 10 80180667 80180775 109 - 1.745 1.829 0.283
ENSMUSG00000043822 E022 8.4126392 0.0024260675 0.2514739719 0.8064151 10 80180776 80180876 101 - 0.905 1.034 0.479
ENSMUSG00000043822 E023 49.0151328 0.0013098302 0.1320725823 0.6884960 10 80180877 80180937 61 - 1.650 1.729 0.268
ENSMUSG00000043822 E024 6.7586394 0.0202885886 0.9056091278 0.9956323 10 80180938 80181042 105 - 0.878 0.860 -0.070
ENSMUSG00000043822 E025 5.2714774 0.0110763997 0.3464361691 0.8743181 10 80181043 80181155 113 - 0.730 0.860 0.515
ENSMUSG00000043822 E026 40.8070632 0.0005187352 0.0561845555 0.5191256 10 80181156 80181247 92 - 1.562 1.667 0.360
ENSMUSG00000043822 E027 7.0581117 0.0290648375 0.7334309597 0.9723295 10 80181248 80181250 3 - 0.905 0.860 -0.173
ENSMUSG00000043822 E028 5.2696137 0.0734664416 0.6610301812 0.9581733 10 80181251 80181346 96 - 0.750 0.832 0.325
ENSMUSG00000043822 E029 81.4846578 0.0006111162 0.2418445811 0.8044216 10 80181347 80181537 191 - 1.879 1.926 0.158
ENSMUSG00000043822 E030 26.6768947 0.0008027945 0.8624333586 0.9888424 10 80181538 80181953 416 - 1.427 1.415 -0.043
ENSMUSG00000043822 E031 4.7490587 0.0075098873 0.0959664345 0.6317038 10 80183116 80183171 56 - 0.818 0.565 -1.061
ENSMUSG00000043822 E032 5.7460276 0.0032149811 0.4075091330 0.8946505 10 80183172 80183390 219 - 0.849 0.737 -0.444
ENSMUSG00000043822 E033 35.0303687 0.0033229856 0.7975763352 0.9811210 10 80183391 80183459 69 - 1.532 1.548 0.057
ENSMUSG00000043822 E034 15.1325322 0.0012717468 0.0053159456 0.1490984 10 80183460 80183689 230 - 1.267 0.997 -0.970
ENSMUSG00000043822 E035 34.5823936 0.0005640624 0.0003686565 0.0226976 10 80183690 80184189 500 - 1.600 1.367 -0.800
ENSMUSG00000043822 E036 30.2064291 0.0036184927 0.2450913676 0.8044216 10 80184190 80184346 157 - 1.446 1.526 0.274

Help

Please Click HERE to learn more details about the results from DEXseq.