ENSMUSG00000055436

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENSMUST00000069025 ENSMUSG00000055436 Control shVgll3 Srsf11 protein_coding protein_coding 85.64649 77.80564 93.48735 1.454541 0.1365313 0.2648654 3.551554 0.000000 7.103109 0.0000000 4.1686741 9.4743365 0.03803333 0.0000000 0.07606667 0.07606667 0.617440452 0.001348282 FALSE  
ENSMUST00000072875 ENSMUSG00000055436 Control shVgll3 Srsf11 protein_coding protein_coding 85.64649 77.80564 93.48735 1.454541 0.1365313 0.2648654 9.355631 10.798202 7.913060 0.2604509 0.6083492 -0.4479968 0.11173333 0.1388667 0.08460000 -0.05426667 0.001348282 0.001348282 FALSE  
ENSMUST00000152274 ENSMUSG00000055436 Control shVgll3 Srsf11 protein_coding retained_intron 85.64649 77.80564 93.48735 1.454541 0.1365313 0.2648654 17.149435 16.060740 18.238131 0.2831379 0.8624261 0.1833123 0.20086667 0.2067000 0.19503333 -0.01166667 0.970665669 0.001348282 FALSE  
MSTRG.15602.3 ENSMUSG00000055436 Control shVgll3 Srsf11 protein_coding   85.64649 77.80564 93.48735 1.454541 0.1365313 0.2648654 25.274243 22.312445 28.236040 0.7207034 1.4039285 0.3395536 0.29465000 0.2873000 0.30200000 0.01470000 0.970665669 0.001348282 FALSE  
MSTRG.15602.5 ENSMUSG00000055436 Control shVgll3 Srsf11 protein_coding   85.64649 77.80564 93.48735 1.454541 0.1365313 0.2648654 5.841333 9.427650 2.255016 1.1695387 2.2550156 -2.0589066 0.07251667 0.1209667 0.02406667 -0.09690000 0.483660534 0.001348282 FALSE  
MSTRG.15602.7 ENSMUSG00000055436 Control shVgll3 Srsf11 protein_coding   85.64649 77.80564 93.48735 1.454541 0.1365313 0.2648654 6.197929 4.263558 8.132300 0.8136247 1.4767916 0.9299985 0.07091667 0.0548000 0.08703333 0.03223333 0.858854479 0.001348282 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand shVgll3 Control log2fold_Control_shVgll3
ENSMUSG00000055436 E001 4.6149658 0.0039026602 0.285781211 0.83279887 3 157716110 157716280 171 - 0.811 0.659 -0.617
ENSMUSG00000055436 E002 27.6472207 0.0008771068 0.227868588 0.80038253 3 157716281 157716555 275 - 1.418 1.496 0.266
ENSMUSG00000055436 E003 1162.1164414 0.0016325096 0.243090675 0.80442163 3 157716556 157717139 584 - 3.055 3.075 0.067
ENSMUSG00000055436 E004 726.6095146 0.0001220105 0.021078197 0.32978625 3 157717140 157717505 366 - 2.847 2.876 0.095
ENSMUSG00000055436 E005 109.3031445 0.0008075718 0.329067637 0.86241242 3 157717506 157717530 25 - 2.026 2.058 0.110
ENSMUSG00000055436 E006 523.7356205 0.0008572552 0.860346675 0.98884244 3 157717531 157717837 307 - 2.721 2.715 -0.019
ENSMUSG00000055436 E007 100.6019252 0.0002304230 0.865945216 0.98892123 3 157717838 157717840 3 - 2.009 2.001 -0.029
ENSMUSG00000055436 E008 166.7803812 0.0014494024 0.112416466 0.65653910 3 157717947 157717979 33 - 2.200 2.249 0.166
ENSMUSG00000055436 E009 105.8910749 0.0006638849 0.001715641 0.07128773 3 157717980 157717987 8 - 1.973 2.083 0.371
ENSMUSG00000055436 E010 216.8452573 0.0001465690 0.140115130 0.70296974 3 157717988 157718040 53 - 2.321 2.354 0.111
ENSMUSG00000055436 E011 219.3260917 0.0001399242 0.398997092 0.89021386 3 157718041 157718072 32 - 2.352 2.329 -0.077
ENSMUSG00000055436 E012 207.3119875 0.0001432026 0.130802692 0.68720021 3 157718073 157718085 13 - 2.335 2.295 -0.135
ENSMUSG00000055436 E013 2.3067085 0.0083336610 0.824273625 0.98471741 3 157718086 157718157 72 - 0.535 0.497 -0.183
ENSMUSG00000055436 E014 426.3680698 0.0001325747 0.866509252 0.98892123 3 157718417 157718510 94 - 2.632 2.626 -0.019
ENSMUSG00000055436 E015 125.6599744 0.0012031246 0.049876023 0.49070623 3 157718511 157718512 2 - 2.069 2.136 0.224
ENSMUSG00000055436 E016 21.2529472 0.0091673330 0.237991069 0.80442163 3 157718513 157718533 21 - 1.297 1.396 0.343
ENSMUSG00000055436 E017 2.1446622 0.0080104481 0.094055702 0.62900916 3 157718534 157718784 251 - 0.345 0.624 1.402
ENSMUSG00000055436 E018 239.1336807 0.0004832898 0.319275914 0.85525295 3 157719589 157719626 38 - 2.369 2.391 0.074
ENSMUSG00000055436 E019 308.8170205 0.0010060348 0.517242693 0.93149289 3 157719627 157719678 52 - 2.483 2.497 0.047
ENSMUSG00000055436 E020 0.6659784 0.3926215448 0.595822532 0.95169375 3 157721955 157721958 4 - 0.282 0.133 -1.357
ENSMUSG00000055436 E021 393.8367355 0.0032219482 0.816036942 0.98411089 3 157721959 157722090 132 - 2.593 2.598 0.017
ENSMUSG00000055436 E022 0.8209761 0.0174091240 0.794152809 0.98063190 3 157722091 157722150 60 - 0.281 0.234 -0.353
ENSMUSG00000055436 E023 189.7592575 0.0001453977 0.136246886 0.69812355 3 157723447 157723528 82 - 2.298 2.256 -0.138
ENSMUSG00000055436 E024 8.6964573 0.0270200051 0.449732698 0.91349987 3 157723529 157723751 223 - 1.030 0.929 -0.375
ENSMUSG00000055436 E025 12.3762920 0.0044246083 0.335310441 0.86618188 3 157724724 157724835 112 - 1.166 1.068 -0.354
ENSMUSG00000055436 E026 193.7157705 0.0001905215 0.510337102 0.93083264 3 157724949 157725027 79 - 2.297 2.277 -0.066
ENSMUSG00000055436 E027 128.3560349 0.0001739063 0.854951368 0.98867271 3 157725028 157725067 40 - 2.114 2.106 -0.028
ENSMUSG00000055436 E028 68.6478556 0.0007071110 0.440184985 0.91153903 3 157725068 157725076 9 - 1.858 1.821 -0.123
ENSMUSG00000055436 E029 165.0390952 0.0030704320 0.832625585 0.98548395 3 157727013 157727062 50 - 2.216 2.221 0.017
ENSMUSG00000055436 E030 171.6752774 0.0052713931 0.369326119 0.87563375 3 157727597 157727649 53 - 2.219 2.254 0.120
ENSMUSG00000055436 E031 128.1142404 0.0003094882 0.607128062 0.95334770 3 157727650 157727689 40 - 2.103 2.117 0.046
ENSMUSG00000055436 E032 272.5711888 0.0002691382 0.126187228 0.67814909 3 157728478 157728566 89 - 2.421 2.452 0.106
ENSMUSG00000055436 E033 110.1923575 0.0106233558 0.587806141 0.95124454 3 157728567 157728587 21 - 2.028 2.063 0.115
ENSMUSG00000055436 E034 209.1314579 0.0001471259 0.897450634 0.99563225 3 157728588 157728879 292 - 2.321 2.321 0.002
ENSMUSG00000055436 E035 202.4542112 0.0022562418 0.997442156 1.00000000 3 157728880 157728996 117 - 2.309 2.306 -0.010
ENSMUSG00000055436 E036 103.9748986 0.0008840771 0.192541185 0.76845676 3 157728997 157729045 49 - 2.043 1.991 -0.173
ENSMUSG00000055436 E037 896.8257860 0.0007787328 0.001719866 0.07128773 3 157729046 157729759 714 - 2.977 2.921 -0.187
ENSMUSG00000055436 E038 153.5971314 0.0001798139 0.377077083 0.87961444 3 157729760 157729868 109 - 2.200 2.172 -0.095
ENSMUSG00000055436 E039 361.2027981 0.0029495649 0.466237066 0.91864397 3 157729869 157730334 466 - 2.569 2.544 -0.086
ENSMUSG00000055436 E040 61.5314013 0.0045900598 0.913946229 0.99729780 3 157730335 157730373 39 - 1.793 1.797 0.016
ENSMUSG00000055436 E041 58.5701738 0.0041170477 0.970068284 1.00000000 3 157730374 157730398 25 - 1.775 1.772 -0.012
ENSMUSG00000055436 E042 1214.7344194 0.0013678975 0.046883533 0.47879770 3 157730399 157732162 1764 - 3.102 3.060 -0.138
ENSMUSG00000055436 E043 146.5658579 0.0021081479 0.924589693 0.99915476 3 157732163 157732361 199 - 2.170 2.165 -0.019
ENSMUSG00000055436 E044 215.5927797 0.0001552316 0.245991666 0.80442163 3 157732362 157732495 134 - 2.322 2.348 0.086
ENSMUSG00000055436 E045 6.0965147 0.0031438840 0.048945378 0.48612309 3 157735822 157736454 633 - 0.949 0.692 -1.009
ENSMUSG00000055436 E046 4.7641608 0.0037375268 0.175537016 0.75672932 3 157736455 157737088 634 - 0.667 0.849 0.734
ENSMUSG00000055436 E047 243.5742414 0.0072368407 0.869431574 0.98919635 3 157737089 157737285 197 - 2.384 2.390 0.022
ENSMUSG00000055436 E048 11.1929470 0.0017318462 0.663823601 0.95817326 3 157737286 157737403 118 - 1.066 1.106 0.147
ENSMUSG00000055436 E049 2.4596936 0.0739800406 0.362538771 0.87540223 3 157737628 157737703 76 - 0.451 0.624 0.815
ENSMUSG00000055436 E050 65.5321179 0.0007794882 0.662702262 0.95817326 3 157742153 157742276 124 - 1.813 1.830 0.057

Help

Please Click HERE to learn more details about the results from DEXseq.